Protective Effect of Escin Against Kidney Injury: Histopathological and Biochemical Evaluations

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dc.contributor.authorMustafa Cengiz
dc.contributor.authorBetül Peker Cengiz
dc.contributor.authorAlanna Teixeira Andrade
dc.contributor.authorAdnan Ayhanci
dc.date.accessioned2025-01-13T07:07:55Z
dc.date.available2025-01-13T07:07:55Z
dc.date.issued2024-11-25
dc.departmentFakülteler, Eğitim Fakültesi, Matematik ve Fen Bilimleri Eğitimi Bölümü
dc.description.abstractThe purpose of the current study was to find out whether escin (ES) safeguarded experimental rats against cyclophosphamide (CP)-induced kidney injury. Twenty-four rats were randomly divided into four groups (n = 6). After the examination, histological and biochemical analyses were performed to assess the alterations in kidney tissue. According to histologic and biochemical analyses, renal tissue in the CP group suffered significant damage by CP. There was a significant improvement in histological damage in the group receiving CP+ES together. This suggests that ES significantly protects the kidney’s functional characteristics. The present study concludes by highlighting histological and biochemical studies to illustrate the ability of ES to cure kidney injury caused by CP and its influence on the relationship between oxidative stress, apoptosis, and renal failure. © 2024 by the authors.
dc.identifier.citationCengiz, M., Peker Cengiz, B., Teixeira Andrade, A., & Ayhanci, A. (2024). Protective Effect of Escin Against Kidney Injury: Histopathological and Biochemical Evaluations. Current Issues in Molecular Biology, 46(12), 13471-13481.
dc.identifier.doi10.3390/cimb46120804
dc.identifier.issn1467-3045
dc.identifier.scopus2-s2.0-85213473309
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://hdl.handle.net/20.500.12604/8427
dc.identifier.wosWOS:001383764700001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakScopus
dc.institutionauthorCengiz, Mustafa
dc.institutionauthorid0000-0003-3692-8532
dc.publisherMDPI AG
dc.relation.ispartofCurrent Issues in Molecular Biology
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcyclophosphamide
dc.subjectescin
dc.subjecthistological alternations
dc.subjectoxidative stress
dc.titleProtective Effect of Escin Against Kidney Injury: Histopathological and Biochemical Evaluations
dc.typejournal-article
oaire.citation.issue12
oaire.citation.volume46

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