Protective Effect of Escin Against Kidney Injury: Histopathological and Biochemical Evaluations
Yükleniyor...
Tarih
2024-11-25
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
MDPI AG
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The purpose of the current study was to find out whether escin (ES) safeguarded experimental rats against cyclophosphamide (CP)-induced kidney injury. Twenty-four rats were randomly divided into four groups (n = 6). After the examination, histological and biochemical analyses were performed to assess the alterations in kidney tissue. According to histologic and biochemical analyses, renal tissue in the CP group suffered significant damage by CP. There was a significant improvement in histological damage in the group receiving CP+ES together. This suggests that ES significantly protects the kidney’s functional characteristics. The present study concludes by highlighting histological and biochemical studies to illustrate the ability of ES to cure kidney injury caused by CP and its influence on the relationship between oxidative stress, apoptosis, and renal failure. © 2024 by the authors.
Açıklama
Anahtar Kelimeler
cyclophosphamide, escin, histological alternations, oxidative stress
Kaynak
Current Issues in Molecular Biology
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
Sayı
Künye
Cengiz, M., Peker Cengiz, B., Teixeira Andrade, A., & Ayhanci, A. (2024). Protective Effect of Escin Against Kidney Injury: Histopathological and Biochemical Evaluations. Current Issues in Molecular Biology, 46(12), 13471-13481.
