Scopus İndeksli Yayınlar Koleksiyonu
Bu koleksiyon için kalıcı URI
Güncel Gönderiler
Öğe The use of food in children's books: A review(Peter Lang AG, 2024-12-10) Koç,FatmaThe use of food in children's books: A reviewÖğe Strong associations between the FGF-2 gene and productivity traits of Holstein-Friesian dairy cattle(Elsevier BV, 2025-03) Mustafa Kibar; İbrahim AytekinSustainability in dairy cattle farms depends on the efficiency of milk yield and reproductive traits. Thus, this study aimed to investigate the effect of the FGF-2/Csp6I gene and major environmental factors on these traits in Holstein-Friesian cattle. A total of 212 whole blood samples were collected from the Vena coccygea of cattle and the data obtained from these samples were used in all statistical analyses. Then, the restriction fragment length polymorphism (RFLP) method (determination of genotypes) was conducted and programs including PopGene (allele and genotype frequencies), Minitab (association analyses) and MTDFREML (variance components and genetic parameters) were used. Alleles A (0.4269) and G (0.5731) as well as genotypes AA (0.174), AG (0.505) and GG (0.321) were found, indicating that the population is polymorphic and in Hardy-Weinberg equilibrium (P > 0.05). The effect of the Csp6I polymorphism of FGF-2 gene on peak milk yield (PMY) (P < 0.01); lactation milk yield (LMY), milking time (MT), 305-day and 200-day lactation milk yield (LMY305 and LMY200), average daily milk yield (ADMY) (P < 0.05); 100-day lactation milk yield (LMY100), age of using in first breeding (AUFB) and number of inseminations per conception (NIPC) (P < 0.10) were significant. The heritability of milk yield traits and the correlation between direct and maternal heritability for reproductive traits were high. Furthermore, the breeding value of PMY was higher for the AA genotype (0.745 ± 0.292) than for the AG genotype (−0.268 ± 0.171) (P < 0.05). As a result, the A allele and AA genotype for the FGF-2/Csp6I gene had an increasing effect on milk yield without compromising reproductive performance in Holstein-Friesian dairy cattle.Öğe Modelling of the tumor growth under oncolytic virotherapy with piecewise differential operators: The effects of combinations of specialist viruses(Qom University of Technology, 2024) Araz, Seda İğret; Denk, ElifThis study proposes to modify a mathematical model of virotherapy inducing cytokine IL-12 and co-stimulatory molecule 4-1BB ligand release with the concept of piecewise derivatives with the aim of analyzing the effects of treatment combinations on tumor growth. In addition to the equilibrium points for the tumor model, the solutions of the model have been proven to be positive. For the model under investigation, the basic reproduction number has been calculated to examine the transmission potential of oncolytic viruses. A method based on Newton polynomials is presented for the numerical solution of the model with piecewise derivative and the numerical simulations for the piecewise model have been depicted for different values of fractional orders. A significant aspect of this study involves analyzing the influence of different dosing strategies, including a single dose and varied doses at different time intervals, on virotherapy through the application of piecewise derivatives. To achieve our aim, we present numerical simulations for the tumor growth model with piecewise derivatives. Simulations show that viral oncolytic plays a crucial role in reducing tumor size but an increase in stimulation of cytotoxic T cells can lead to a short-term reduction followed by a more rapid relapse. Furthermore, thanks to the model modified with the concept of piecewise derivative to examine the effects of using different doses at different times on tumor growth, it has been possible to conclude that the virus dose given at the time when the tumor size started to increase after the first dose caused a decrease in tumor size. Finally, according to the assumptions of the considered model and the outputs of the mathematical tools used, it can be concluded that tumor growth seems to be controllable through treatment combinations in virotherapy.Öğe Predictors of Breastfeeding Success in Postpartum Period: Delivery Type, Postpartum Support, and Postpartum Depression(Ataturk Universitesi, 2024-12-23) Ayşegül Kılıçlı; Sidar GülThis study aimed to investigate the association between delivery type, postpartum support need and postpartum depression on breastfeeding success in the first postpartum month. Methods: This study, conducted between August 8, 2022 and August 31, 2023, was comparative, prospective and cross‐sectional. Sample consisted of 300 women (150 vaginal, 150 cesarean section). Data were collected using Descriptive Information Form, Postpartum Support Questionnaire, Edinburgh Postpartum Depression Scale, and Bristol Breastfeeding Assessment Tool. Multiple linear regression was used to identify the predictors of breastfeeding success. Results: Those who did not received sufficient support rate was 50.7%, the presence of postpartum depression was 54.0%, and the mean breastfeeding success score was 6.4±0.9 which was moderate. Cesarean delivery (β=‐0.149, p<.01), increased need for postpartum support (β=‐0.203, p<.01) and postpartum depression (β=0.261, p<.01) were significant predictors which were explaining 21.0% of total variance in breastfeeding success. The breastfeeding success of cesarean section mothers who did not have postpartum depression but received inadequate support decreased by 20.3% compared to vaginal birth mothers. Mothers who gave birth by caesarean section, did not receive postpartum support and were at risk of postpartum depression had the lowest breastfeeding success. Conclusion: Cesarean section, postpartum support, and postpartum depression are factors that significantly affect breastfeeding success. Therefore, breastfeeding counselling services for mothers in the postpartum care process should be planned and implemented individually to address mode of delivery, need for postpartum support and postpartum depression.Öğe Investigation of the presence of Chlamydia spp., Mycoplasma spp. and Moraxella ovis in infectious keratoconjunctivitis cases in sheep and goats in Siirt province and evaluation of clinical findings(Polish Academy of Sciences Chancellery, 2024-06-12) A. Gulaydin; O. Gulaydin; M.B. Akgul; N. Sindak; O. YildirimInfectious keratoconjunctivitis is an infectious disease that negatively affects animal welfare causing systemic or local clinical signs in small ruminants and causes significant economic losses in herds. It is important to determine the etiologic agent causing the infection in the development of the protection and control strategies against the disease. The aim of this study was to determine the presence of infectious keratoconjunctivitis cases in small ruminants raised in Siirt province in Türkiye. Infectious keratoconjunctivitis was graded according to the symptoms determined by clinical examination. The presence of Chlamydia spp., Mycoplasma spp. and Moraxella ovis was investigated by PCR in swab samples obtained from the animals with keratoconjunctivitis. Infectious keratoconjunctivitis was detected in 263 (19.86%) of 1324 animals examined in the study. Of the animals with infectious keratoconjunctivitis, 163 (61.97%) were sheep and 100 (38.02%) were goats. The detection rate of infectious keratoconjunctivitis was higher in sheep than goats. In 56 (21.29%), 109 (41.44%), 67 (25.47%), and 31 (11.78%) of the cases, findings of stage 1, 2, 3, and 4 infectious keratoconjunctivitis were detected, respectively. Of the eye swab samples taken from 263 animals with infectious keratoconjunctivitis, 5 (1.90%) were positive for Mycoplasma spp. and 6 (2.28%) were positive for M. ovis. It was determined that the distribution of the bacterial agents varied according to the stage of infectious keratoconjunctivitis. No statistically significant correlation was found in the distribution of bacterial agents among identified samples according to species, sex, age, and infectious keratoconjunctivitis stage of the animals. It was thought that the data obtained in the study would contribute to the studies for protection and control by determining the incidence and aetiology of infectious keratoconjunctivitis cases observed in small ruminants. © 2024 The Authors. This is an open access article under the CC BY-NC-ND 4.0 license (https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en), which allows re-users to copy and distribute the material in any medium or format in unadapted form and for noncommercial purposes, and only so long as attribution is given to the creator.Öğe First Report of Zoonotic Cryptosporidium parvum Subtype IIaA15G2R1 in Dogs in Türkiye(Pakistan Veterinary Journal, 2024) Ayan, Adnan; Celik, Burcak Aslan; Celik, Ozgur Yasar; Akyildiz, Gurkan; Kilinc, Ozlem Orunc; Ayan, Ozge Oktay; Uslu, UgurCryptosporidium (C.) is an opportunistic protozoan causing gastrointestinal illness in both humans and animals, leading to acute or chronic diarrhea and even death. The study aimed to investigate the prevalence and subtyping of Cryptosporidium spp. in shelter dogs in Van province, Türkiye. For microscopic identification of this parasite, a total of 300 fecal samples were collected and stained with Kinyoun's acid-fast method. For molecular analysis, the positive samples were subjected to DNA extraction and SSU rRNA gene of Cryptosporidium spp. was amplified using nested PCR. The microscopic examination revealed a 4.67% prevalence of Cryptosporidium spp. Sequence analysis indicated all samples were positive to C. parvum. In addition, GP60 gene was also amplified and C. parvum subtypes IIaA15G2R1 was confirmed by analyzing the obtained sequences. All the sequences of SSU rRNA and GP60 were deposited in GenBank. To our knowledge, Cryptosporidium parvum subtypes IIaA15G2R1 have been reported first time in dogs in Türkiye. It is recommended to implement control strategies by awareness campaign, preventing stray dogs from freely entering public areas, and proper disposal of dog feces.Öğe The validity and reliability study of the Turkish version of the Ethical Awareness Scale(Informa UK Limited, 2024-12-28) Gülcan Eyüboğlu; Nevin Doğan; Arnel Böke Kiliçli; Zehra Göçmen Baykara; Aimee MillikenThe heightened focus on patient safety and the quality of nursing care in intensive care units underscores the necessity for reliable tools to evaluate nurses’ ethical awareness. This study was aimed to evaluate the psychometric properties of the Turkish version of the Ethical Awareness Scale in a sample of intensive care nurses. Data were collected from 249 intensive care nurses in Türkiye using the Turkish version of the 18-item Ethical Awareness Scale. The data were then analyzed using Rasch analysis. The Turkish version of the Ethical Awareness Scale demonstrated unidimensionality and an acceptable fit for the Rasch model. The person reliability and item reliability were 0.63 and 0.92, respectively. The Turkish version of the Ethical Awareness Scale was found to be a psychometrically valid and reliable instrument for measuring the ethical awareness levels of intensive care nurses.Öğe Effect of different solvents on hydrogen production from hydrolysis of potassium borohydride with a new and active Ni-based catalyst synthesized by green synthesis(Elsevier BV, 2024-12) Ömer Şahin; Selma Ekinci; Mehmet Sait İzgi; Erhan OnatIn this study, a novel Ni-based catalyst supported on carbon quantum dots (CQDs), synthesized from caffeine via a green hydrothermal method was developed to enhance hydrogen generation. The effects of different solvents, including water, and ethanol, on the catalyst's performance were explored. The results demonstrate that the Ni@CQDs catalyst prepared in ethanol exhibited superior hydrogen production rates due to improved nickel dispersion and higher surface area, as confirmed by BET, XPS, and XRD analyses. Ethanol was found to effectively modify the catalyst, resulting in faster H₂ conversion compared to water. The HGR values obtained with catalysts synthesized in water and ethanol were 4662, and 12262 mL min−1g−1, respectively. The study also investigated the impact of KOH concentration, catalyst loading, KBH4 concentration, and temperature on the hydrolysis process. The Ni@CQDs catalyst synthesized in ethanol achieved optimal performance at higher KBH₄ and KOH concentrations, producing 100% H2 yield over six reusability cycles with minimal loss of catalytic efficiency. Thermodynamic analysis using the Arrhenius and Eyring-Polanyi equations indicated that the catalyst in ethanol had a lower activation energy, enhancing the hydrolysis reaction rate. The Ni@CQDs (ethanol) catalyst exhibited a significantly higher TOF of 1696 h⁻1 at 4% KBH4 concentration and a lower activation energy (Ea) of 33.78 kJ mol−1 compared to the Ni@CQDs (water) catalyst, which had a TOF of 601.5 h⁻1 at 2% KBH4 concentration and an Ea of 38.93 kJ mol−1, indicating superior catalytic efficiency with ethanol as the solvent.Öğe A Theological Analysis of Biological Determinism Claims in the Context of Epigenetics and Brain Plasticity(Istanbul University, 2024-03-13) Seyithan CanSeveral theoretical studies have investigated biological determinism. First, it leaves no room for divine intervention in the various spheres of human activity. Second, it asserts that heredity significantly influences human behavior. This notion emphasizes the idea that humans possess both freedom and wildness. According to biological determinism, behavior is predetermined by DNA, reducing physiological brain activity. Consequently, what is commonly perceived to be human freedom is illusory. If an individual’s actions are not a result of their own will, the issue of justice arises from the rewards and punishments that God metes out in response to human behavior. To address the theological dilemmas posed by these assertions of biological determinism, we sought to ground human freedom, will, and responsibility within the framework of God’s justice, by drawing on insights from epigenetics and brain plasticity. However, can recent developments in genetic science comprehensively elucidate human behavior, potentially revealing the freedom we once believed we possessed to be an illusion? Answering this question was one of the primary objectives of this study.Öğe Evaluation of the Antioxidant, Antidiabetic and Anti-Alzheimer Effects of Capsella bursa-pastoris-Polyphenolic Profiling by LC-MS/MS(ACG Publications, 2024-12-26) İlhami Gülçin; Hasan Karageçili; Tuğba Polat; Mustafa Abdullah Yılmaz; Mehmet Fidan; Cengiz KaraismailoğluCapsella bursa-pastoris species of the Capsella herb were examined in this study for sreening of antioxidant, antidiabetic and anti-Alzheimer effects. Traditionally, people consumed C. bursa-pastoris against famine and satisfy their hunger. C. bursa-pastoris species have been shown to have utility as food, medicine, and industrial materials after extensive investigation. The antioxidant properties of methanol and water extracts of C. bursa-pastoris species were assessed using; Fe3+-2,4,6-tris(2-pyridyl)-S-triazine (TPTZ), ferric (Fe3+), and cupric (Cu2+) iobs reducing assays, as well as 2,2’-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid radical (ABTS•+) and N,N-dimethyl-p-phenylenediamine (DMPD) radical scavenging activities. The antioxidant and reducing capacity of C. bursa-pastoris species aerial parts water and methanol extracts were compared with standard antioxidants. The phenolic and flavonoid contents in methanol and water extracts of C. bursa-pastoris species were measured 6.86 to 12.00 mg GAE/g and 61.67 to 145.0 mg QE/g, respectively. The inhibitions of effects of water and methanol extract of C. bursa-pastoris species against α-amylase, and acetylcholinesterase (AChE) enzymes were investigated. The IC50 values were found as 168.6 to 238.6 μg/mL against α-amylase and 19.0 to 20.9 μg/mL against AChE. The number of fenolik compounds in both extracts of C. bursa-pastoris species were recorded using LC-MS/MS. The major phenolic and flavonoid components detected in methanol extract of C. bursa-pastoris were quinic acid (22.629 mg/g), chlorogenic acid (3.211 mg/g), rutin (1.930 mg/g), hesperidin (0.893 mg/g), and isoquercitrin (0.783 mg/g). In a similar order, quinic acid (11.356 mg/g), cyranoside (9.463 mg/g), chlorogenic acid (6.072 mg/g), hesperidin (5.912 mg/g), and isoquercitrin (5.364 mg/g) were found as plentyfull pehenolic antioxidants in methanolic extract. The results clearly demonstrated that polyphenolic antioxidants-rich ingredients of the aerial parts of C. bursa-pastoris species are biological phenolic comounds have persuasive usage in the medication of diabetes and Alzheimer's diseases.Öğe Theoretical investigation on fractal–fractional nonlinear ordinary differential equations(Elsevier BV, 2025-08) Abdon Atangana; Seda İğret ArazIn this study, we examine the existence and uniqueness conditions of the solutions of the nonlinear fractal-fractional differential equations. Particular emphasis is placed on four cases: exponential decay, power law, generalized Mittag-Leffler kernels and the Delta-Dirac function. Our first contribution is the formulation of some basic inequalities inspired from Gronwall inequality setting up a solid foundation for our analysis to follow. We subsequently carefully obtain the maximal and minimal solutions in each scenario, providing a complete picture of their structure. Finally we show convergence of four different successive approximation schemes, validating their applicability in the various contexts. This is an important finding that adds to the growing literature on the use of fractional calculus in complex dynamical systems.Öğe Facile preparation of sulfonated carbon particles with pomegranate peels as adsorbent for enhanced methylene blue adsorption from aqueous solutions(Springer Science and Business Media LLC, 2024-01-19) Yaşar Genel; İlyas Genel; Cafer SakaIn this study, in the first stage, activated carbon (AC) is produced from pomegranate peels, which are commonly found in Turkey, by pyrolysis after impregnation with NaOH (PPAC). In the second stage, the surface properties of the obtained PPAC sample are further improved by the sulfonation modification process with sulphuric acid (PPAC-S) for selective MB adsorption. For the characterization of the obtained samples, XRD, FTIR, SEM, nitrogen adsorption/desorption and EDS analyses were performed. Additionally, the zero charge points (pHzpc) of these samples were also determined. The isotherm, kinetic, and thermodynamic properties of the MB adsorption process with PPAC-S were examined. The qe values obtained for MB adsorption with PPAC and PPAC-S samples were found to be 98.79 mg/g and 199.18 mg/g, respectively. There is an increase of 100% in MB adsorption with the sulfonated PPAC adsorbent. Maximum adsorption capacity values of MB with the Langmuir model at temperatures of 298, 308, and 318 degrees C were 212.7, 216.9, and 245.1 mg/g, respectively. Additionally, the mechanism of MB adsorption onto PPAC-S was also attempted to be elucidated.Öğe Investigation of growth traits in Turkish Merino lambs using multi-locus GWAS approaches: Middle Anatolian Merino(Springer Science and Business Media LLC, 2024-12-19) Yalçın Yaman; Şükrü DOĞAN; Mesut KIRBAŞ; A. Taner ÖNALDI; Yavuz KALThis study explored the genetic basis of growth traits in Middle Anatolian Merino lambs using multi-locus genome-wide association study (GWAS) analyses. Descriptive statistics indicated moderate heritability (h² = 0.363) for birth weight (BW) and (h² = 0.309) for weaning weight (WW), both statistically significant (p < 0.001). Strong genetic correlations were observed between WW and BW (rG = 0.922) and WW and Kleiber ratio (KR, rG = 0.896), implying that simultaneous improvements may be possible through targeted selection. Five multi-locus methods (mrMLM, FASTmrMLM, pLARmEB, FASTmrEMMA, and ISIS EM-BLASSO) were used to identify the polygenic basis of the traits. For BW and WW, 20 and 18 significant SNPs (LOD ≥ 5) were detected, respectively, with some SNPs co-detected by multiple methods. In contrast, only 10 significant SNPs were identified for KR, all exclusively by the ISIS EM-BLASSO approach. Pathway analyses within ± 100 Kb of associated SNPs revealed genes and pathways influencing these traits, which could be leveraged in future breeding programs for enhanced growth performance. The identified SNPs, particularly those associated with BW and WW traits, could facilitate genomic selection if validated in larger and more diverse populations.Öğe Determination of the effect of magnesium applications on yield, fiber quality and chlorophyll content in cotton(The Journal of Ege University Faculty of Agriculture, 2024-12-16) Emine Karademir; Emine SebatObjective: The objective of this investigation was to determine the effects of different applications of magnesium (Mg) on yield, yield attributes, fiber quality traits, chlorophyll content, and normalized difference vegetative index in cotton. Material and Methods: In this study 7 different Mg applications were applied, and MAY 455 cotton cultivar and Magnesium Sulphate were used. Results: It was determined that seed cotton yield, number of nodes of first fruiting branches, number of vegetative branches, number of bolls, height/node ratio, boll weight, fiber strength, uniformity, elongation, and spinning consistency index were affected by magnesium applications. The highest value in terms of the number of bolls, number of vegetative branches and height/node ratio was observed with 200 cc/da Mg application at the squaring stage, while the highest seed cotton yield was recorded with 200 cc/da Mg at flowering stage and Mg application lead to increase 60 kg/da in seed cotton yield. The highest spinning consistency index and uniformity was obtained with 600 cc/da Mg application at the squaring stage, other quality traits were affected by different doses or application stages. Conclusion: Applying green parts during the squaring or flowering period may be advantageous since magnesium has a positive impact on the yield and certain fiber quality of cotton.Öğe Investigation of growth traits in Turkish Merino lambs using multi-locus GWAS approaches: Middle Anatolian Merino(Springer Science and Business Media LLC, 2024-12-19) Yalçın Yaman; Şükrü DOĞAN; Mesut KIRBAŞ; A. Taner ÖNALDI; Yavuz KALThis study explored the genetic basis of growth traits in Middle Anatolian Merino lambs using multi-locus genome-wide association study (GWAS) analyses. Descriptive statistics indicated moderate heritability (h² = 0.363) for birth weight (BW) and (h² = 0.309) for weaning weight (WW), both statistically significant (p < 0.001). Strong genetic correlations were observed between WW and BW (rG = 0.922) and WW and Kleiber ratio (KR, rG = 0.896), implying that simultaneous improvements may be possible through targeted selection. Five multi-locus methods (mrMLM, FASTmrMLM, pLARmEB, FASTmrEMMA, and ISIS EM-BLASSO) were used to identify the polygenic basis of the traits. For BW and WW, 20 and 18 significant SNPs (LOD ≥ 5) were detected, respectively, with some SNPs co-detected by multiple methods. In contrast, only 10 significant SNPs were identified for KR, all exclusively by the ISIS EM-BLASSO approach. Pathway analyses within ± 100 Kb of associated SNPs revealed genes and pathways influencing these traits, which could be leveraged in future breeding programs for enhanced growth performance. The identified SNPs, particularly those associated with BW and WW traits, could facilitate genomic selection if validated in larger and more diverse populations.Öğe Determination of germination and seedling characteristics of common grasspea (Lathyrus sativus L.) genotypes under salt stress(The Journal of Ege University Faculty of Agriculture, 2024-12-16) Serhan Kaya; Semih AçıkbaşObjective: In this study, the aim was to determine the germination and seedling development responses of common grasspea (Lathyrus sativus L.) genotypes under salt stress and to identify genotypes sensitive or tolerant to salinity. Materials and Methods: The research was conducted at the Field Crops Laboratory of the Faculty of Agriculture, Siirt University, under controlled conditions at 25±1°C. The plant material of the study consists of 2 cultivars and 8 genotypes. The study investigated the doses of NaCl at 0, 50, 100, 150, and 200 mM. The laboratory experiment was conducted by a completely randomized factorial design with four replications. Results: The increase in salt levels significantly (p<0.01) affected the germination and seedling characteristics of grasspea genotypes. It was determined that common grasspea genotypes were significantly affected by increasing salt concentrations with regard to germination parameters starting from the 50 mM salt dose. Regarding seedling parameters, grasspea genotypes were affected by salt concentrations beyond 50 mM in relation to seedling length and seedling dry weight, while other seedling parameters were negatively impacted even at the lowest salt dose. Conclusion: When all examined parameters were considered together, the Sel 668 genotype stood out for its tolerance to salinity and its performance in germination and seedling development.Öğe Utilisation of green nitrogen-doped biomass-based hierarchical porous activated carbon particles for enhancement of electrochemical energy storage performance(Elsevier BV, 2025-02) İlyas Genel; Yavuz Yardım; Cafer SakaActivated carbon particles were obtained from rosehip wood-based carbon precursor by chemical activation with potassium hydroxide (RHAC). After this pyrolysis process, nitrogen-doped hierarchical porous carbon was prepared by ammonia activation (N-doped RHAC). The prepared carbonaceous materials were designed as an electrode for a supercapacitor. Standard electrochemical analyses were performed. The specific capacitance (Cs) of RHAC/GCE was determined to be 25 F/g at 2.5 mV/s and 23 F/g at 0.2 A/g. In contrast, the N-doped RHAC/GCE demonstrated significantly higher Cs values of 119 F/g at 2.5 mV/s and 121 F/g at 0.2 A/g. According to CV and GCD measurements, the N-doped RHAC material exhibited approximately a fivefold increase in specific capacitance compared to the RHAC-based electrode. A specific capacitance retention rate of 94.6 % was obtained after 1000 cycles at a current density of 1.6 A/g. The surface properties and characteristics of the obtained materials were carried out by SEM, nitrogen adsorption, Raman, FTIR, EDS and XPS analyses. EDS and XPS analyses showed that N atom doping was successful. This study suggests that rosehip tree biomass-based N atom doped carbon material is suitable for supercapacitors as an electrode.Öğe Modeling and analysis of dengue transmission in fuzzy-fractional framework: a hybrid residual power series approach(Springer Science and Business Media LLC, 2024-12-28) Mubashir Qayyum; Qursam Fatima; Ali Akgül; Murad Khan HassaniThe current manuscript presents a mathematical model of dengue fever transmission with an asymptomatic compartment to capture infection dynamics in the presence of uncertainty. The model is fuzzified using triangular fuzzy numbers (TFNs) approach. The obtained fuzzy-fractional dengue model is then solved and analyzed through fuzzy extension of modified residual power series algorithm, which utilizes residual power series along with Laplace transform. Numerical analysis has also been performed in this study and obtained results are shown as solutions and residual errors for each compartment to ensure the validity. Graphical analysis depict the model’s behavior under varying parameters, illustrating contrasting trends for different values of and examining the impacts of transmission and recovery rates on dengue model in uncertain environment. The current findings highlighted the effectiveness of proposed uncertainty in epidemic system dynamics, offering new insights with potential applications in other areas of engineering, science and medicine.Öğe Protective Effect of Escin Against Kidney Injury: Histopathological and Biochemical Evaluations(MDPI AG, 2024-11-25) Mustafa Cengiz; Betül Peker Cengiz; Alanna Teixeira Andrade; Adnan AyhanciThe purpose of the current study was to find out whether escin (ES) safeguarded experimental rats against cyclophosphamide (CP)-induced kidney injury. Twenty-four rats were randomly divided into four groups (n = 6). After the examination, histological and biochemical analyses were performed to assess the alterations in kidney tissue. According to histologic and biochemical analyses, renal tissue in the CP group suffered significant damage by CP. There was a significant improvement in histological damage in the group receiving CP+ES together. This suggests that ES significantly protects the kidney’s functional characteristics. The present study concludes by highlighting histological and biochemical studies to illustrate the ability of ES to cure kidney injury caused by CP and its influence on the relationship between oxidative stress, apoptosis, and renal failure. © 2024 by the authors.Öğe A novel technique using integral transforms and residual functions for nonlinear partial fractional differential equations involving Caputo derivatives.(Public Library of Science, 2024) Khan, Zareen A; Riaz, Muhammad Bilal; Liaqat, Muhammad Imran; Akgül, AliFractional nonlinear partial differential equations are used in many scientific fields to model various processes, although most of these equations lack closed-form solutions. For this reason, methods for approximating solutions that occasionally yield closed-form solutions are crucial for solving these equations. This study introduces a novel technique that combines the residual function and a modified fractional power series with the Elzaki transform to solve various nonlinear problems within the Caputo derivative framework. The accuracy and effectiveness of our approach are validated through analyses of absolute, relative, and residual errors. We utilize the limit principle at zero to identify the coefficients of the series solution terms, while other methods, including variational iteration, homotopy perturbation, and Adomian, depend on integration. In contrast, the residual power series method uses differentiation, and both approaches encounter difficulties in fractional contexts. Furthermore, the effectiveness of our approach in addressing nonlinear problems without relying on Adomian and He polynomials enhances its superiority over various approximate series solution techniques.
