Immunohistochemical Distribution of Heat Shock Proteins 27, 60, 70 and 90 in the Placenta of Goats in the Second and Third Trimester of Pregnancy

Basit Öğe Kaydı
dc.contributor.authorBanu Kandil
dc.date.accessioned2025-03-17T10:49:56Z
dc.date.available2025-03-17T10:49:56Z
dc.date.issued2025-02-27
dc.departmentFakülteler, Veteriner Fakültesi, Temel Bilimler Bölümü
dc.description.abstractDetermining the immunoexpression of HSPs in the placenta may contribute to the understanding of pregnancy physiology and immunotolerance mechanisms. This study aimed to determine the distribution of HSP27, HSP60, HSP70 and HSP90 in the placenta of goats. Tissue samples were taken from the placentomal and interplacentomal regions of the pregnant uterus of 12 goats, comprising 6 s and 6 third trimesters. Following routine histological procedures, immunohistochemical staining was performed on tissue sections. In the interplacentomal region, HSP27, HSP60, HSP70 and HSP90 in luminal and glandular epithelial, stromal and smooth muscle cells did not show differences between the second and third trimesters (p > 0.05). In the placentomal region, HSP27 and HSP60 in syncytial plaques and HSP27, HSP60, HSP70, and HSP90 in maternal stromal cells did not change as the pregnancy progressed (p > 0.05). There was no difference in HSP27, HSP60 and HSP90 in fetal stromal cells between the second and third trimesters (p > 0.05). HSP27 and HSP90 were positive in both trophoblast cells, HSP60 was positive in binucleate trophoblast cells, and HSP70 was positive in mononucleate trophoblast cells. In the third trimester compared with the second trimester, HSP27 was decreased (p < 0.05), while HSP90 in mononucleate and binucleate trophoblast cells did not show a difference (p > 0.05). HSP70 did not change in mononucleate trophoblast cells (p > 0.05), but HSP60 was increased in binucleate trophoblast cells (p < 0.05) as the pregnancy progressed. In conclusion, this study showed that HSPs had similar immunoexpression patterns in the interplacentomal region but different immunoexpression patterns in the placentomal region of the goat placenta
dc.identifier.citationKandil, B. (2025). Immunohistochemical Distribution of Heat Shock Proteins 27, 60, 70 and 90 in the Placenta of Goats in the Second and Third Trimester of Pregnancy. Anatomia, Histologia, Embryologia, 54(2), e70027.
dc.identifier.doi10.1111/ahe.70027
dc.identifier.issn0340-2096
dc.identifier.issn1439-0264
dc.identifier.issue2
dc.identifier.pmid40013551
dc.identifier.scopus2-s2.0-85219516352
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1111/ahe.70027
dc.identifier.urihttps://hdl.handle.net/20.500.12604/8566
dc.identifier.volume54
dc.identifier.wosWOS:001433781800001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakScopus
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorKandil, Banu
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofAnatomia, Histologia, Embryologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectgoat
dc.subjectheat shock protein
dc.subjectimmunohistochemistry
dc.subjectplacenta
dc.subjectpregnancy
dc.titleImmunohistochemical Distribution of Heat Shock Proteins 27, 60, 70 and 90 in the Placenta of Goats in the Second and Third Trimester of Pregnancy
dc.typejournal-article
oaire.citation.issue2
oaire.citation.volume54

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Banu-Kandil-2025.pdf
Boyut:
3.03 MB
Biçim:
Adobe Portable Document Format
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.17 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
2) Makale
PubMed İndeksli Yayın Koleksiyonu
WOS İndeksli Yayınlar Koleksiyonu