Analytical Methods on Determination in Pharmaceuticals and Biological Materials of Chloroquine as Available for the Treatment of COVID-19

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dc.authoridSAKA, Cafer/0000-0003-2534-5921
dc.contributor.authorSaka, Cafer
dc.date.accessioned2024-12-24T19:28:14Z
dc.date.available2024-12-24T19:28:14Z
dc.date.issued2022
dc.departmentSiirt Üniversitesi
dc.description.abstractWith the outbreak caused by the severe acute respiratory syndrome coronavirus (COVID-19), people's health and existing economies on a global scale are seriously threatened. Currently, most of the countries all over the world are studying extensively to better understand the antimalarial chloroquine (CQ) and hydroxychloroquine (HCQ) for therapeutic purposes due to the COVID-19 outbreak. However, CQ and HCQ can have serious side effects, from psychiatric effects to sudden death. Therefore, a faster and more effective detection method is needed to monitor drug concentrations. In this review, a large study was conducted on the detection techniques and quantitative determination methods of CQ and its related metabolites. In this review, chromatography, electrophoresis, electroanalytical, spectroscopic, and immunological methods for CQ and related metabolites are discussed extensively. It is hoped that a better understanding of the CQ used for therapeutic purposes in the COVID-19 outbreak will be provided.
dc.identifier.doi10.1080/10408347.2020.1781592
dc.identifier.endpage34
dc.identifier.issn1040-8347
dc.identifier.issn1547-6510
dc.identifier.issue1
dc.identifier.pmid32628049
dc.identifier.scopus2-s2.0-85087656163
dc.identifier.scopusqualityQ1
dc.identifier.startpage19
dc.identifier.urihttps://doi.org/10.1080/10408347.2020.1781592
dc.identifier.urihttps://hdl.handle.net/20.500.12604/6979
dc.identifier.volume52
dc.identifier.wosWOS:000546279000001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofCritical Reviews in Analytical Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectAnalytical methods
dc.subjectchloroquine
dc.subjectCOVID-19
dc.subjectdetermination
dc.titleAnalytical Methods on Determination in Pharmaceuticals and Biological Materials of Chloroquine as Available for the Treatment of COVID-19
dc.typeReview Article

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