Protective properties of kefir on burn wounds of mice that were infected with S. aureus, P. auroginasa and E. coli

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dc.authoridCETIK YILDIZ, Songul/0000-0002-7855-5343
dc.authoridCENGIZ, Mustafa/0000-0002-6925-8371
dc.contributor.authorYildiz, Songul Cetik
dc.contributor.authorDemir, Cemil
dc.contributor.authorCengiz, Mustafa
dc.contributor.authorAyhanci, Adnan
dc.date.accessioned2024-12-24T19:30:03Z
dc.date.available2024-12-24T19:30:03Z
dc.date.issued2019
dc.departmentSiirt Üniversitesi
dc.description.abstractBurns and burn wounds are very sensitive to infections and cause a large amount of death worldwide. Although burn wound is sterile at the beginning, because of the risk factors such as prolonged hospital stay, immune suppression and burn affecting large surface area, colonisation with Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli occur. For the burn therapy, one of the most important ways is to control bacterial infections. A probiotic fermented milk product kefir has antioxidant, antimicrobial, antiinflammatory, anticancer and various health promoting features. This study aims to examine possible protective properties of kefir which was used on the burn wounds that were infected with S. aureus, P. auroginasa and E. coli. Swiss albino / Balb-c mice were seperated into four groups: (1) used as control group, (2) second-degree burn model+ burn wounds were infected with P.aeruginosa + S.aureus + E.coli, (3) second-burn wounds were treated with sterile pads dressed with kefir and (4) second-degree burn+burn wounds were infected with P. aeruginosa + S.aureus +E.coli before being treated with sterile pads dressed with kefir. The serum biochemical results verified the histopathological results and our findings showed that kefir is an effective product with cell-protecting properties.
dc.description.sponsorshipMardin Artuklu University - Coordination Unit of Scientific Research Project [MAU-BAP-15-SHMYO-23]
dc.description.sponsorshipThis study was supported by Mardin Artuklu University - Coordination Unit of Scientific Research Project (MAU-BAP-15-SHMYO-23). This study was approved by the by the Rectorate of Eskisehir Osmangazi University Local Ethics Committee of Animal Experiments with the number 618-2/30.11.2017.
dc.identifier.doi10.14715/cmb/2019.65.7.11
dc.identifier.endpage65
dc.identifier.issn0145-5680
dc.identifier.issn1165-158X
dc.identifier.issue7
dc.identifier.pmid31880519
dc.identifier.scopus2-s2.0-85077246669
dc.identifier.scopusqualityQ4
dc.identifier.startpage60
dc.identifier.urihttps://doi.org/10.14715/cmb/2019.65.7.11
dc.identifier.urihttps://hdl.handle.net/20.500.12604/7358
dc.identifier.volume65
dc.identifier.wosWOS:000489886900011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherC M B Assoc
dc.relation.ispartofCellular and Molecular Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241222
dc.subjectSecond-degree burn
dc.subjectKefir
dc.subjectWound healing
dc.subjectInfections
dc.subjectS.aureus
dc.subjectP.aeruginosa
dc.subjectE.coli
dc.subjectMice
dc.titleProtective properties of kefir on burn wounds of mice that were infected with S. aureus, P. auroginasa and E. coli
dc.typeArticle

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