Investigation of the effects of propofol and sevoflurane anesthesia on oxidant-antioxidant status and biochemical parameters in Turkish hair goats

Basit Öğe Kaydı
dc.contributor.authorAli Gülaydın
dc.contributor.authorKıvanç İrak
dc.contributor.authorNihat Şındak
dc.contributor.authorMustafa Barış Akgül
dc.contributor.authorÖzgür Yaşar Çelik
dc.contributor.authorOnur Yıldırım
dc.contributor.authorMaruf Yılmaz
dc.contributor.authorErman Gülendağ
dc.date.accessioned2025-02-25T13:27:45Z
dc.date.available2025-02-25T13:27:45Z
dc.date.issued2025-02-17
dc.departmentFakülteler, Veteriner Fakültesi, Klinik Bilimler Bölümü
dc.description.abstractObjective: To investigate the effects of propofol and sevoflurane anesthesia on the oxidant-antioxidant status and biochemical parameters in Turkish hair goats. Methods: The study was conducted from February 15 through March 15, 2024. Seven clinically healthy female Turkish hair goats aged 1 to 2 years with an average live weight of 29.95 (26.1 to 33.8) kg were included. A bolus of propofol (6 mg/kg) was injected IV. The goats were placed in the sternoabdominal position and administered 1% to 3% sevoflurane with 100% oxygen for 2 hours with the help of a vaporizer. Blood samples were collected before and after the administration of propofol and at the 15th, 30th, 60th, and 120th minutes after the start of sevoflurane administration in nonanticoagulated tubes. The oxidant-antioxidant status (serum total antioxidant status, total oxidant status, paraoxonase activity, and arylesterase activity) and biochemical parameters (levels of glucose, AST, GGT, ALT, ALP, LDH, creatine kinase, amylase, lipase, creatinine, urea, uric acid, high-density lipoprotein, low-density lipoprotein, total protein, albumin, total bilirubin, direct bilirubin, magnesium, chlorine, calcium, iron, sodium, phosphorus, and potassium) were evaluated. The heart rate, respiratory rate, and body temperature of the goats were measured using a bedside monitor. Results: Arylesterase activity increased with sevoflurane administration. Changes were observed in heart rate and body temperature as well as in the levels of glucose, creatine kinase, urea, total bilirubin, and potassium at different time intervals of propofol-sevoflurane administration. Conclusions: Propofol-sevoflurane anesthesia has no adverse effects on oxidant-antioxidant status in Turkish hair goats. Clinical relevance: The evaluation of heart rate and body temperature, as well as glucose, creatine kinase, urea, total bilirubin, and potassium levels, must be considered in propofol-sevoflurane anesthesia protocol.
dc.identifier.citationGülaydın, A., İrak, K., Şındak, N., Akgül, M. B., Çelik, Ö. Y., Yıldırım, O., ... & Gülendağ, E. (2025). Investigation of the effects of propofol and sevoflurane anesthesia on oxidant-antioxidant status and biochemical parameters in Turkish hair goats. American Journal of Veterinary Research, 1(aop), 1-7.
dc.identifier.doi10.2460/ajvr.24.10.0309
dc.identifier.issn0002-9645
dc.identifier.issn1943-5681
dc.identifier.pmid39965329
dc.identifier.urihttps://doi.org/10.2460/ajvr.24.10.0309
dc.identifier.urihttps://hdl.handle.net/20.500.12604/8539
dc.indekslendigikaynakPubMed
dc.institutionauthorGülaydın, Ali
dc.institutionauthorİrak, Kıvanç
dc.institutionauthorŞındak, Nihat
dc.institutionauthorAkgül, Mustafa Barış
dc.institutionauthorÇelik, Özgür Yaşar
dc.institutionauthorYıldırım, Onur
dc.institutionauthorYılmaz, Maruf
dc.institutionauthorGülendağ, Erman
dc.institutionauthorid0000-0002-7200-1040
dc.institutionauthorid0000-0001-9765-0330
dc.institutionauthorid0000-0002-9365-9925
dc.language.isoen
dc.publisherAmerican Veterinary Medical Association (AVMA)
dc.relation.ispartofAmerican Journal of Veterinary Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTurkish hair goat
dc.subjectanesthesia
dc.subjectoxidant/antioxidant status
dc.subjectpropofol
dc.subjectsevoflurane
dc.titleInvestigation of the effects of propofol and sevoflurane anesthesia on oxidant-antioxidant status and biochemical parameters in Turkish hair goats
dc.typejournal-article

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Ali-Gülaydın-2025.pdf
Boyut:
545.46 KB
Biçim:
Adobe Portable Document Format
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.17 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

PubMed İndeksli Yayın Koleksiyonu
2) Makale