The effect of Some Boron Derivatives on Kanamycin Resistance and Survival of E. coli and P. aeruginosa in Lake Water

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dc.authoridDarcan, Cihan/0000-0003-0205-3774
dc.contributor.authorDarcan, Cihan
dc.contributor.authorKahyaoglu, Mustafa
dc.date.accessioned2024-12-24T19:34:04Z
dc.date.available2024-12-24T19:34:04Z
dc.date.issued2012
dc.departmentSiirt Üniversitesi
dc.description.abstractObjective To study MIC value of 7 boron derivatives namely [Boric acid (H3BO3), Anhydrous Borax (Na2B4O7), Sodium Borate (NaBO2), Diammonium Tetraborate (NH4)(2)B4O7, Sodium Perborate (NaBO3), Boron Trioxide (B2O3), Potassium Tetraborate (K2B4O7)] on E. coli and P. aeruginosa and their effects on survival of bacteria in lake water and resistance against kanamycin antibiotic. Methods MIC values of Boron derivatives and antibiotic were studied by broth microdilution method. The effect of boron derivatives on survival of bacteria in lake water were also determined with plate count. Results Sodium perborate was determined as the most effective substance among the studied substances. Effectiveness increased as temperature increased. E. coli was more affected from P. aeruginosa in 8 mg/mL sodium perborate concentration in lake water. Moreover, it was determined that MIC value of kanamycin antibiotic decreased 200 times by especially treating P. aeruginosa with sodium perborate in lake water. However, it can be stated that this change in resistance did not arise from microorganisms. Conclusion Sodium perborate solution can be used supportedly in kanamycin antibiotic applications for P. aeruginosa. Future studies are necessary to explore the relation between sodium perborate and kanamycin which is effective on P. aeruginosa in lake water.
dc.description.sponsorshipNational Boron Research Institute (BOREN)-Turkey [2009-C-0214]
dc.description.sponsorshipThis study is supported by 2009-C-0214 numbered project of National Boron Research Institute (BOREN)-Turkey.
dc.identifier.doi10.3967/0895-3988.2012.04.014
dc.identifier.endpage482
dc.identifier.issn0895-3988
dc.identifier.issue4
dc.identifier.pmid23026529
dc.identifier.scopus2-s2.0-84866997459
dc.identifier.scopusqualityQ3
dc.identifier.startpage476
dc.identifier.urihttps://doi.org/10.3967/0895-3988.2012.04.014
dc.identifier.urihttps://hdl.handle.net/20.500.12604/8411
dc.identifier.volume25
dc.identifier.wosWOS:000308786000014
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherChinese Center Disease Control & Prevention
dc.relation.ispartofBiomedical and Environmental Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectBoron
dc.subjectLake water
dc.subjectKanamycin
dc.subjectE. coli
dc.subjectP. aeruginosa
dc.titleThe effect of Some Boron Derivatives on Kanamycin Resistance and Survival of E. coli and P. aeruginosa in Lake Water
dc.typeArticle

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