Lack of evidence for association between the leptin/Sau3AI gene and milk yield traits in Holstein Friesian dairy cattle

dc.authoridOZKAN, ILKER ALI/0000-0002-5715-1040
dc.authoridAytekin, Ibrahim/0000-0001-7769-0685
dc.authoridKibar, Mustafa/0000-0002-1895-019X
dc.contributor.authorKibar, Mustafa
dc.contributor.authorAytekin, Ibrahim
dc.date.accessioned2024-12-24T19:27:49Z
dc.date.available2024-12-24T19:27:49Z
dc.date.issued2023
dc.departmentSiirt Üniversitesi
dc.description.abstractThis study aimed to investigate the effect of leptin gene polymorphism and some environmental factors on milk production traits. Blood samples from 212 Holstein Friesian dairy cattle reared on a private farm were used. The intron 2 region of the leptin gene was digested with Sau3A I restriction enzyme using the PCR-RFLP method. A and B alleles and AA, AB, and BB genotype frequencies for the Sau3A I polymorphism were determined as 0.8821 and 0.1179, and 0.764, 0.236 and 0.000, respectively. Chi-square analysis revealed that the leptin gene polymorphism followed the Hardy-Weinberg equilibrium, including the absence of animals with the BB genotype. The effect of leptin gene polymorphism on all milk production traits was insignificant. For milk production traits, direct heritability ( h(a)(2) ) varied between 0.03 +/- 0.283 (for the dry period) and 0.50 +/- 0.183 (for milk conductivity). Regarding the milking time (MT), the estimated breeding values (EBVs) of cattle with the AA genotype were higher than the AB genotype ( P < 0.05). As a result of this study, in the selection program, allele or genotype could not be suggested as a marker for milk yield characteristics except for the possible exception of milking time and its relationship to mastitis incidence.
dc.identifier.doi10.1017/S0022029923000717
dc.identifier.endpage342
dc.identifier.issn0022-0299
dc.identifier.issn1469-7629
dc.identifier.issue4
dc.identifier.pmid38186204
dc.identifier.scopus2-s2.0-85182211354
dc.identifier.scopusqualityQ1
dc.identifier.startpage339
dc.identifier.urihttps://doi.org/10.1017/S0022029923000717
dc.identifier.urihttps://hdl.handle.net/20.500.12604/6808
dc.identifier.volume90
dc.identifier.wosWOS:001142830100001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCambridge Univ Press
dc.relation.ispartofJournal of Dairy Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectBreeding value
dc.subjectHolstein Friesian
dc.subjectleptin
dc.subjectmilk yield
dc.subjectselection
dc.titleLack of evidence for association between the leptin/Sau3AI gene and milk yield traits in Holstein Friesian dairy cattle
dc.typeArticle

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