The effect of evening primrose oil (Oenothera biennis) on the level of adiponectin and some biochemical parameters in rats with fructose induced metabolic syndrome

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dc.authoridCIBUK, SALIH/0000-0001-5427-4929
dc.contributor.authorMert, Handan
dc.contributor.authorIrak, Kivanc
dc.contributor.authorCibuk, Salih
dc.contributor.authorYildirim, Serkan
dc.contributor.authorMert, Nihat
dc.date.accessioned2024-12-24T19:28:17Z
dc.date.available2024-12-24T19:28:17Z
dc.date.issued2022
dc.departmentSiirt Üniversitesi
dc.description.abstractThe effect of evening primrose oil on adiponectin level and some biochemical parameters in model of fructose-induced metabolic syndrome were investigated. The rats were divided into 4 groups: control, evening primrose oil, fructose, fructose + evening primrose oil. Body weight, daily feed and water consumptions and systolic blood pressures of animals were measured. At the end of trial, blood samples were taken, livers were excised and histopathological examination was performed. Glucose, uric acid, triglyceride, T.cholesterol, LDL, HDL, VLDL, ALT, AST, ALP, LDH, adiponectin, insulin, IL-6, TNF-alpha, TAC, and TOS levels were analysed. Some analysed parameters and systolic blood pressure of fructose + evening primrose oil group decreased significantly compared to fructose group and adiponectin, TAC, and HDL levels were significantly increased. As conclusion, evening primrose oil can be considered as antioxidant agent by reducing oxidative stress, increasing adiponectin levels and insulin sensitivity, anti-inflammatory properties, exhibiting anti-atherogenic effect by regulating dyslipidemia and systolic blood pressure.
dc.description.sponsorshipVan YYU Directory of Scientific Research Project [TSA-2018-6903]
dc.description.sponsorshipThis research was supported by the Van YYU Directory of Scientific Research Project under project number TSA-2018-6903.
dc.identifier.doi10.1080/13813455.2020.1781900
dc.identifier.endpage1547
dc.identifier.issn1381-3455
dc.identifier.issn1744-4160
dc.identifier.issue6
dc.identifier.pmid32594769
dc.identifier.scopus2-s2.0-85087492518
dc.identifier.scopusqualityQ1
dc.identifier.startpage1539
dc.identifier.urihttps://doi.org/10.1080/13813455.2020.1781900
dc.identifier.urihttps://hdl.handle.net/20.500.12604/7006
dc.identifier.volume128
dc.identifier.wosWOS:000549473700001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofArchives of Physiology and Biochemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectMetabolic syndrome
dc.subjectfructose
dc.subjectevening primrose oil
dc.subjectadiponectin
dc.subjectoxidant-antioxidant status
dc.titleThe effect of evening primrose oil (Oenothera biennis) on the level of adiponectin and some biochemical parameters in rats with fructose induced metabolic syndrome
dc.typeArticle

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