Differential in vitro inhibition studies of some cerium vanadate derivatives on xanthine oxidase

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dc.authoridKAYA, Mustafa Oguzhan/0000-0002-8592-1567
dc.contributor.authorKaya, Mustafa Oguzhan
dc.contributor.authorKaya, Yesim
dc.contributor.authorCelik, Gulsah
dc.contributor.authorKurtulus, Figen
dc.contributor.authorArslan, Oktay
dc.contributor.authorGuler, Ozen Ozensoy
dc.date.accessioned2024-12-24T19:30:59Z
dc.date.available2024-12-24T19:30:59Z
dc.date.issued2015
dc.departmentSiirt Üniversitesi
dc.description.abstractIn this preliminary study, a new series of some cerium vanadate derivatives have been investigated as new type of inhibitors of xanthine oxidase (XO; E.C 1.17.3.2). XO is a superoxide-producing enzyme found normally in serum and the lungs, and its activity is concerned with several important health problems such as gout, severe liver damage, vascular dysfunction and injury, oxidative eye injury and renal failure. In this study, we present a critical overview of the effects of these novel type agents on XO with comparing the efficacy and safety profiles of allopurinol, the efficient classical inhibitor of XO.
dc.identifier.doi10.3109/14756366.2014.920837
dc.identifier.endpage289
dc.identifier.issn1475-6366
dc.identifier.issn1475-6374
dc.identifier.issue2
dc.identifier.pmid24964345
dc.identifier.scopus2-s2.0-84926474700
dc.identifier.scopusqualityQ1
dc.identifier.startpage286
dc.identifier.urihttps://doi.org/10.3109/14756366.2014.920837
dc.identifier.urihttps://hdl.handle.net/20.500.12604/7755
dc.identifier.volume30
dc.identifier.wosWOS:000352274500018
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofJournal of Enzyme Inhibition and Medicinal Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241222
dc.subjectCerium vanadate derivatives
dc.subjectinhibition
dc.subjectxanthine oxidase
dc.titleDifferential in vitro inhibition studies of some cerium vanadate derivatives on xanthine oxidase
dc.typeArticle

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