High Level Production of Extracellular Protease from Bacillus licheniformis ATCC 12759 in Submerged Fermentation

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dc.contributor.authorNurullah, Akcan
dc.date.accessioned2024-12-24T19:33:07Z
dc.date.available2024-12-24T19:33:07Z
dc.date.issued2012
dc.departmentSiirt Üniversitesi
dc.description.abstractProduction of extracellular protease by Bacillus licheniformis ATCC 12759 in submerged fermentation was the aim of this study. Various nutrients belonging to three categories, carbon, nitrogen and amino acid sources, were investigated in terms of their effect on the production of extracellular protease by Bacillus licheniformis ATCC 12759. Comparison with the control in media containing the all simple sugars resulted in a decrease in proteolytic activity, while there was significant increase in enzyme yield in the case of the supplementation complex carbon source such as wheat flour and rice flour. Urea, soy flour and sodium nitrate are the best organic and inorganic sources respectively. Among the amino acid sources tested, L-phenylalanine, L-cysteine, Glysine, L-valine, L-tyrosine, L-isoleusine, L-tryptophane and Glutamic acid favored the production respectively. FeSO4, ZnSO4 and CuSO4 inhibited protease production. Maximum protease production (10738.2 +/- 44.2 U/mg) was obtained in a medium containing 0.1% MgSO4 in 24 h 37 degrees C.
dc.identifier.endpage51
dc.identifier.issn2278-4535
dc.identifier.issue3
dc.identifier.scopus2-s2.0-84865265595
dc.identifier.scopusqualityQ4
dc.identifier.startpage46
dc.identifier.urihttps://hdl.handle.net/20.500.12604/7958
dc.identifier.volume7
dc.identifier.wosWOS:000311754600008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherResearch Journal Biotechnology
dc.relation.ispartofResearch Journal of Biotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectBacillus licheniformis ATCC 12759
dc.subjectprotease
dc.subjectsubmerged fermentation
dc.subjectenzyme production
dc.titleHigh Level Production of Extracellular Protease from Bacillus licheniformis ATCC 12759 in Submerged Fermentation
dc.typeArticle

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