Effect of boric acid on some elemental levels on rat's liver and kidney tissues during mercury chloride exposure

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dc.contributor.authorAkkoyun, Hurrem Turan
dc.date.accessioned2024-12-24T19:30:02Z
dc.date.available2024-12-24T19:30:02Z
dc.date.issued2018
dc.departmentSiirt Üniversitesi
dc.description.abstractIn this study, the effect of boric acid on the important trace elements copper (Cu), iron (Fe), zinc (Zn), manganese (Mn) and nickel (Ni) in liver and kidney tissue of rats treated with mercury chloride was investigated. Twenty-four male Wistar albino rats (weighing 200 +/- 300 g) were divided into 3 groups: Control (C), Mercury chloride (HgCl2), Mercury chloride (HgCl2) + boric acid (BA). Iron and copper were decreased whereas Mn, Zn and Ni levels were increased in liver tissue in Hg administered group compared to control. Cu (p<0.01) and Mn (p<0.001) levels were increased in Hg + BA administered group compared to Hg group. Renal tissue Cu (p<0.01), Mn and Zn levels were increased whereas Ni (p<0.05) and Fe levels were decreased in Hg administered group compared to control group. Cu (p<0.001) and Zn (p<0.05) content increased in Hg + BA group compared to control group. As a result, it is thought that boric acid may have an effect on important trace element levels such as copper (Cu), iron (Fe), zinc (Zn), manganese (Mn), nickel (Ni) in case of oxidative stress caused by mercury chloride.
dc.identifier.doi10.14715/cmb/2018.64.13.16
dc.identifier.endpage88
dc.identifier.issn0145-5680
dc.identifier.issn1165-158X
dc.identifier.issue13
dc.identifier.pmid30403601
dc.identifier.scopus2-s2.0-85056381362
dc.identifier.scopusqualityQ4
dc.identifier.startpage84
dc.identifier.urihttps://doi.org/10.14715/cmb/2018.64.13.16
dc.identifier.urihttps://hdl.handle.net/20.500.12604/7354
dc.identifier.volume64
dc.identifier.wosWOS:000449070100016
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherC M B Assoc
dc.relation.ispartofCellular and Molecular Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241222
dc.subjectBoric Acid
dc.subjectMercury Chloride
dc.subjectTrace Elements
dc.subjectLiver
dc.subjectKidney
dc.titleEffect of boric acid on some elemental levels on rat's liver and kidney tissues during mercury chloride exposure
dc.typeArticle

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