Chemical profiling and antioxidant potential of propolis from Pervari, Siirt: discovery of tannic acid and key bioactive compounds

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dc.contributor.authorErkan Sırma
dc.contributor.authorMehmet Fidan
dc.contributor.authorMesut Gök
dc.contributor.authorİbrahim Tegin
dc.contributor.authorMustafa Abdullah Yılmaz
dc.contributor.authorErdal Yabalak
dc.date.accessioned2025-02-03T06:16:17Z
dc.date.available2025-02-03T06:16:17Z
dc.date.issued2025-01-24
dc.departmentFakülteler, Fen-Edebiyat Fakültesi, Biyoloji Bölümü
dc.description.abstractPropolis, a natural product with remarkable therapeutic potential, has gained attention for its antimicrobial, antioxidant, and anti-inflammatory properties. In this study, propolis samples from Sarıyaprak, Kovanağzı, and Çemikari in Pervari, Siirt province, were analysed comprehensively. The evaluation included wax composition, DPPH and FRAP assays, total phenolic and flavonoid content, and pollen analysis. Phytochemical compounds were identified using GC-MS and LC-MS/MS techniques. Among the regions, Çemikari samples exhibited the highest antioxidant activity and phenolic and flavonoid contents, with wax content averaging 60% across all locations. Key compounds identified via RSH-GC/MS included α-pinene, β-pinene, nonadecanal, and nonanal, while GC-MS revealed borneol, sedrenol, and benzyl alcohol. Significant phenolic compounds such as gallic acid, caffeic acid, and tannic acid (reported for the first time in Turkish propolis) were also detected. The high borneol concentration, with its strong anti-inflammatory properties, underscores the unique traits of these samples and their promising antioxidant potential for further research.
dc.identifier.citationSırma, E., Fidan, M., Gök, M., Tegin, İ., Yılmaz, M. A., & Yabalak, E. (2025). Chemical profiling and antioxidant potential of propolis from Pervari, Siirt: discovery of tannic acid and key bioactive compounds. Natural Product Research, 1-14.
dc.identifier.doi10.1080/14786419.2025.2456677
dc.identifier.issn1478-6419
dc.identifier.issn1478-6427
dc.identifier.pmid39854191
dc.identifier.urihttps://doi.org/10.1080/14786419.2025.2456677
dc.identifier.urihttps://hdl.handle.net/20.500.12604/8476
dc.identifier.wosWOS:001405091400001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakWeb of Science
dc.institutionauthorFidan, Mehmet
dc.institutionauthorid0000-0002-0255-9727
dc.publisherInforma UK Limited
dc.relation.ispartofNatural Product Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntioxidant
dc.subjectbiological activity
dc.subjectphytochemical compounds
dc.subjectpropolis
dc.subjecttannic acid.
dc.titleChemical profiling and antioxidant potential of propolis from Pervari, Siirt: discovery of tannic acid and key bioactive compounds
dc.typejournal-article

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