Chemical profiling and antioxidant potential of propolis from Pervari, Siirt: discovery of tannic acid and key bioactive compounds

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Tarih

2025-01-24

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Informa UK Limited

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Propolis, a natural product with remarkable therapeutic potential, has gained attention for its antimicrobial, antioxidant, and anti-inflammatory properties. In this study, propolis samples from Sarıyaprak, Kovanağzı, and Çemikari in Pervari, Siirt province, were analysed comprehensively. The evaluation included wax composition, DPPH and FRAP assays, total phenolic and flavonoid content, and pollen analysis. Phytochemical compounds were identified using GC-MS and LC-MS/MS techniques. Among the regions, Çemikari samples exhibited the highest antioxidant activity and phenolic and flavonoid contents, with wax content averaging 60% across all locations. Key compounds identified via RSH-GC/MS included α-pinene, β-pinene, nonadecanal, and nonanal, while GC-MS revealed borneol, sedrenol, and benzyl alcohol. Significant phenolic compounds such as gallic acid, caffeic acid, and tannic acid (reported for the first time in Turkish propolis) were also detected. The high borneol concentration, with its strong anti-inflammatory properties, underscores the unique traits of these samples and their promising antioxidant potential for further research.

Açıklama

Anahtar Kelimeler

Antioxidant, biological activity, phytochemical compounds, propolis, tannic acid.

Kaynak

Natural Product Research

WoS Q Değeri

Q3

Scopus Q Değeri

Cilt

Sayı

Künye

Sırma, E., Fidan, M., Gök, M., Tegin, İ., Yılmaz, M. A., & Yabalak, E. (2025). Chemical profiling and antioxidant potential of propolis from Pervari, Siirt: discovery of tannic acid and key bioactive compounds. Natural Product Research, 1-14.