Age-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino Rats

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dc.contributor.authorKetani, Şennur
dc.contributor.authorKarakoç, Zelal
dc.contributor.authorKetani, Muzaffer Aydın
dc.contributor.authorKılınç, Mehmet
dc.date.accessioned2017-04-27T09:30:06Z
dc.date.available2017-04-27T09:30:06Z
dc.date.issued2016
dc.departmentBelirleneceken_US
dc.description.abstractICAM-1 which is expressed by endothelial cells and leukocytes are observed as first markers in diseases such as transplant rejection, diabetes and atherosclerosis and in infections caused by various pathogens. In the present study, it is aimed to reveal the age-related changes in the expression of ICAM-1 on rats. Therefore, a total of 30 albino rats were taken at the age of 6, 18 and 24 months without gender discrimination. Rats were fed with standard pellet feed during the study. Afterwards, rats were sacrificed and tissue samples were collected from their rats, and the samples were evaluated under the light microscope by staining with immnunohistochemical method. It was determined that the expression of both aortic endothelial cells and endothelial cells in the media layer had been significantly increased based on the age.en_US
dc.identifier.scopus2-s2.0-85011347384
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://hdl.handle.net/20.500.12604/404
dc.identifier.wosWOS:000395669600049
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofseries34;4
dc.relation.publicationcategoryUluslararası Hakemli Dergi Makalesien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKG_20241224
dc.source.urihttp://dx.doi.org/10.4067/S0717-95022016000400049
dc.subjectICAM-1; Rat; Aortic endothelium; Age.en_US
dc.titleAge-Related Changes in the Expression of ICAM-1 in the Aorta of Wistar Albino Ratsen_US
dc.typeArticleen_US
dcterms.publisherInternational Journal of Morphology

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