Analytical Strategies for the Determination of Norepinephrine Reuptake Inhibitors in Pharmaceutical Formulations and Biological Fluids

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dc.authoridSAKA, Cafer/0000-0003-2534-5921
dc.contributor.authorSaka, Cafer
dc.date.accessioned2024-12-24T19:28:13Z
dc.date.available2024-12-24T19:28:13Z
dc.date.issued2016
dc.departmentSiirt Üniversitesi
dc.description.abstractNorepinephrine reuptake inhibitors (NRIs) are a class of antidepressant drugs that act as reuptake inhibitors for the neurotransmitters norepinephrine and epinephrine. The present review provides an account of analytical methods published in recent years for the determination of NRI drugs. NRIs are atomoxetine, reboxetine, viloxazine and maprotiline. NRIs with less activity at other sites are mazindol, bupropion, tapentadol, and teniloxazine. This review focuses on the analytical methods including chromatographic, spectrophotometric, electroanalytical, and electrophoresis techniques for NRI analysis from pharmaceutical formulations and biological samples. Among all of the published methods, liquid chromatography with UV-vis or MS-MS detection is the most popular technique. The most the common sample preparation techniques in the analytical methods for NRIs include liquid-liquid extraction and solid-phase extraction. Besides the analytical methods for single components, some of the simultaneous determinations are also included in this review.
dc.identifier.doi10.1080/10408347.2014.948679
dc.identifier.endpage66
dc.identifier.issn1040-8347
dc.identifier.issn1547-6510
dc.identifier.issue1
dc.identifier.pmid26857446
dc.identifier.scopus2-s2.0-84958044417
dc.identifier.scopusqualityQ1
dc.identifier.startpage40
dc.identifier.urihttps://doi.org/10.1080/10408347.2014.948679
dc.identifier.urihttps://hdl.handle.net/20.500.12604/6974
dc.identifier.volume46
dc.identifier.wosWOS:000370298000004
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofCritical Reviews in Analytical Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectanalytical methods
dc.subjectnorepinephrine reuptake inhibitors
dc.subjectantidepressant drugs
dc.subjectpharmaceutical formulations
dc.subjectbiological fluids
dc.titleAnalytical Strategies for the Determination of Norepinephrine Reuptake Inhibitors in Pharmaceutical Formulations and Biological Fluids
dc.typeReview Article

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