Box-Behnken design based optimization of phenolic extractions from Polygonum equisetiforme roots linked to its antioxidant and antibacterial efficiencies

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dc.authoridRahman, Md Atikur/0000-0001-6779-9599
dc.contributor.authorElgudayem, Farah
dc.contributor.authorAldiyab, Abdullah
dc.contributor.authorAlbalawi, Marzough Aziz
dc.contributor.authorOmran, Awatif
dc.contributor.authorKafkas, Nesibe Ebru
dc.contributor.authorSaghrouchni, Hamza
dc.contributor.authorVar, Isil
dc.date.accessioned2024-12-24T19:33:29Z
dc.date.available2024-12-24T19:33:29Z
dc.date.issued2023
dc.departmentSiirt Üniversitesi
dc.description.abstractPurposeThe Polygonum equisetifome is a prospective plant source of high protein, unsaturated fatty acids, and useful safe bioactive molecules. Therefore, the aim of this study was to optimize the ultrasonic aqueous extraction of phenols from P. equisetifome roots using Box-Behnken design based statistical modeling, and to evaluate the antioxidant and antibacterial efficiencies of P. equisetifome root extracts against pathogenic bacteria. MethodsIn this study, the box-behnken design was used to optimize the extraction of phenols. The extraction temperature (30-70 degrees C), ultrasound assisted extraction (UAE) time (1-9 min), and liquid-solid ratio (35-45 mL/g) were investigated as the factors that influence the phenolic yield (Y1) and their DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging activity (Y2). ResultsThe optimal conditions for both responses were 50 degrees C, 5 min, and 40 mL/g. At these conditions, Y1 reached its maximum to be 45.321 mg GAE/g dry weight and Y2 to be 120.354 mu mol Trolox/g dry weight. The P. equisetifome roots contained water soluble phenol, high anthocyanin, and condensed tannins. Interestingly, the P. equisetifome extracts showed a relation to its antioxidant and antibacterial activities, FRAP (Ferric-reducing/antioxidant power), and ABTS scavenging activity were determined. The morphological and physico-chemical features of the extract were analyzed using SEM-EDX, FT-IR, and minimum inhibitory concentration (MIC) was analyzed against several pathogenic bacteria. The antibacterial activity of the extract showed that the extract is more efficient against Staphylococcus aureus, while the P. equisetifome extracts showed efficient MIC against S. aureus, followed by Bacillus cereus. SuggestionsThe relation of P. equisetifome extracts to its antioxidant, and antibacterial efficiencies open a new avenue of their potential uses in the food and pharmaceutical industries.
dc.identifier.doi10.3389/fsufs.2023.1141207
dc.identifier.issn2571-581X
dc.identifier.scopus2-s2.0-85150375668
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3389/fsufs.2023.1141207
dc.identifier.urihttps://hdl.handle.net/20.500.12604/8157
dc.identifier.volume7
dc.identifier.wosWOS:000950144800001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherFrontiers Media Sa
dc.relation.ispartofFrontiers in Sustainable Food Systems
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241222
dc.subjectbiological activities
dc.subjectBox-Behnken design
dc.subjectchemical characterization
dc.subjectP
dc.subjectequisetiforme roots
dc.subjectwater-soluble phenolic compounds
dc.subjectultrasonic-assisted extraction
dc.titleBox-Behnken design based optimization of phenolic extractions from Polygonum equisetiforme roots linked to its antioxidant and antibacterial efficiencies
dc.typeArticle

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