Evaluation of one-shot vaccination protocol for suppressing reproductive functions in rams using encapsulated ovalbumin-LHRH-7 protein

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dc.authoridUlker, Hasan/0000-0002-7776-3925
dc.contributor.authorYilmaz, Ayhan
dc.contributor.authorKarakus, Ferda
dc.contributor.authorHakan, Bunyamin
dc.contributor.authorStormo, Keith
dc.contributor.authorCengiz, Firat
dc.contributor.authorUlker, Hasan
dc.date.accessioned2024-12-24T19:30:32Z
dc.date.available2024-12-24T19:30:32Z
dc.date.issued2018
dc.departmentSiirt Üniversitesi
dc.description.abstractThe objective of study were to determine the effectiveness of Ovalbumin-LHRH-7 (OL) protein administered with cytosine guanine (CpG) adjuvant and Incomplete Freund's Adjuvant (IFA), and used one-shot immunization (single-dose vaccination) protocol in which booster dose included in microspheres in rams. Fifty ram lambs at about a year old were used. Treatment groups receiving Ovalbumin LHRH and control contained 10 animals. They were stratified according to age (weeks), live weight and scrotal circumference size, and were randomly assigned to five groups. Scrotal circumference, sexual activities and the numbers of rams having sperm in the ejaculate were affected from treatment (P<0.05) depending on the dose and vaccination protocol. However, immunization did not affect live weight changes in any treatment groups (P>0.05). Findings clearly demonstrate that the effects of OL immunization on reproductive traits in yearling rams were prominent when it was administered at higher dose and classical one primary and one booster immunization as free protein form. Also we observed that the effect of higher and single dose of OL protein in encapsulated form on reproductive traits had the partial suppressing. CpG adjuvant along with IFA was proved to be an effective adjuvant and could be suggested to be used and alternative to FCA in hormone immunization.
dc.description.sponsorshipYuzuncu Yil University Research Fund [2007-ZF-B-023]
dc.description.sponsorshipThis study was supported by Yuzuncu Yil University Research Fund (Project no. 2007-ZF-B-023).
dc.identifier.doi10.18805/ijar.v0iOF.8472
dc.identifier.endpage342
dc.identifier.issn0367-6722
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85044991047
dc.identifier.scopusqualityQ3
dc.identifier.startpage337
dc.identifier.urihttps://doi.org/10.18805/ijar.v0iOF.8472
dc.identifier.urihttps://hdl.handle.net/20.500.12604/7570
dc.identifier.volume52
dc.identifier.wosWOS:000430654900002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAgricultural Research Communication Centre
dc.relation.ispartofIndian Journal of Animal Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectLHRH immunization
dc.subjectEncapsulation
dc.subjectSingle shot vaccination
dc.subjectScrotal circumference
dc.subjectSperm production
dc.subjectRam
dc.titleEvaluation of one-shot vaccination protocol for suppressing reproductive functions in rams using encapsulated ovalbumin-LHRH-7 protein
dc.typeArticle

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