Synthesis and Characterization of Bionanomaterials and Evaluation of Their Antioxidant, Antibacterial, and DNA Cleavage Activities

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dc.authoridTarhan, Tuba/0000-0003-2656-4464
dc.authoridDUNDAR, ABDURRAHMAN/0000-0002-7930-1054
dc.contributor.authorTarhan, Tuba
dc.contributor.authorDundar, Abdurrahman
dc.contributor.authorOkumus, Veysi
dc.contributor.authorCulha, Mustafa
dc.date.accessioned2024-12-24T19:24:21Z
dc.date.available2024-12-24T19:24:21Z
dc.date.issued2021
dc.departmentSiirt Üniversitesi
dc.description.abstractIn this study, the hexagonal boron nitride (hBN) (1), poly-levodopa (P-L(DP) (2), P-L(DP) coated hBN (hBN@P(L-DP)) (3), and silver nanoparticles (AgNPs) decorated hBN@P(L-DP) (hBN@P(L-DP)-AgNPs) (4) were synthesized and characterized by multiple spectroscopic techniques. Additionally, their biological properties such as antioxidant, antibacterial, and DNA cleavage activities were determined. It is worth noting that, products 3 and 4 were newly synthesized structures. The antioxidant activities of all the nanomaterials 1, 2, 3, and 4 nanomaterials were investigated using some tests such as DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging and reducing power ability. Among the synthesized nanomaterials, product 2 exhibited the highest radical scavenging (64.8 +/- 1.94 %) and reducing power activity (0.61 +/- 0.017) at a concentration of 200 mg L-1. Product 4 was determined to have antibacterial activity against all three Gram-positive and three Gram-negative test bacteria. In addition, all the nanomaterials were tested for cleavage activity using pBR 322 plasmid DNA, as a result of which it was determined that only product 4 showed the ability of cleavage from both chains of DNA.
dc.identifier.doi10.1002/slct.202004773
dc.identifier.endpage4223
dc.identifier.issn2365-6549
dc.identifier.issue17
dc.identifier.scopus2-s2.0-85107541586
dc.identifier.scopusqualityQ3
dc.identifier.startpage4217
dc.identifier.urihttps://doi.org/10.1002/slct.202004773
dc.identifier.urihttps://hdl.handle.net/20.500.12604/5935
dc.identifier.volume6
dc.identifier.wosWOS:000656879800023
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWiley-V C H Verlag Gmbh
dc.relation.ispartofChemistryselect
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectAntioxidant activity
dc.subjectDNA cleavage activity
dc.subjectL-dopa
dc.subjectNanomaterials
dc.subjectSilver Nanoparticles
dc.titleSynthesis and Characterization of Bionanomaterials and Evaluation of Their Antioxidant, Antibacterial, and DNA Cleavage Activities
dc.typeArticle

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