Biological assays and theoretical density functional theory calculations of Rh(I), Ir(III), and Ru(II) complexes of chiral phosphinite ligand

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dc.authoridbinbay, nil/0000-0002-2488-0378
dc.authoridZazybin, Alexey/0000-0002-6244-9327
dc.authoridISIK, UGUR/0000-0003-1010-9563
dc.authoridAydemir, Murat/0000-0002-4238-5012
dc.authoridRafikova, Khadichakhan/0000-0001-8028-2244
dc.authoridOkumus, Veysi/0000-0002-5505-2700
dc.contributor.authorRafikova, Khadichakhan
dc.contributor.authorBinbay, Nil Ertekin
dc.contributor.authorMeric, Nermin
dc.contributor.authorKerimkulova, Aygul
dc.contributor.authorZazybin, Alexey
dc.contributor.authorBinbay, Veysel
dc.contributor.authorOkumus, Veysi
dc.date.accessioned2024-12-24T19:24:07Z
dc.date.available2024-12-24T19:24:07Z
dc.date.issued2020
dc.departmentSiirt Üniversitesi
dc.description.abstractFour metal complexes, IL-OPPh2-Ru-p-cymene (3), IL-OPPh2-Ru-benzene (4), IL-OPPh2-Ir-Cp* (5), IL-OPPh2-Rh-COD (6), have been evaluated for in vitro antioxidant activity such as 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and reducing power activity. Maximum scavenging activity (71.43%) was obtained with IL-OPPh2-Ru-p-cymene, whereas IL-OPPh2-Rh-COD showed the highest reducing power ability. The complexes were also studied for their antimicrobial activity against three Gram-positive and three Gram-negative bacteria. In addition, DNA binding of the complexes was evaluated using calf thymus DNA. Both Ru(II) complexes exhibited good DNA-binding activity while the other complexes did not have any activity. Furthermore, ab initio quantum calculations of four complexes were also carried out using density functional theory to better understand their chemical behaviors.
dc.identifier.doi10.1002/aoc.5658
dc.identifier.issn0268-2605
dc.identifier.issn1099-0739
dc.identifier.issue7
dc.identifier.scopus2-s2.0-85081753349
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1002/aoc.5658
dc.identifier.urihttps://hdl.handle.net/20.500.12604/5841
dc.identifier.volume34
dc.identifier.wosWOS:000538134500020
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofApplied Organometallic Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectbiological study
dc.subjectDFT calculation
dc.subjectionic liquid
dc.subjectphosphinite
dc.subjectruthenium
dc.titleBiological assays and theoretical density functional theory calculations of Rh(I), Ir(III), and Ru(II) complexes of chiral phosphinite ligand
dc.typeArticle

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