Transition metals of arene derivatives with functionalized ionic liquid: DFT investigation, biological applications and electrochemical behavior of complexes

Basit Öğe Kaydı
dc.authoridbinbay, nil/0000-0002-2488-0378
dc.authoridRafikova, Khadichakhan/0000-0001-8028-2244
dc.contributor.authorRafikova, Khadichakhan
dc.contributor.authorMeric, Nermin
dc.contributor.authorGuzel, Remziye
dc.contributor.authorArslan, Nevin
dc.contributor.authorBinbay, Nil Ertekin
dc.contributor.authorKayan, Cezmi
dc.contributor.authorOkumus, Veysi
dc.date.accessioned2024-12-24T19:27:13Z
dc.date.available2024-12-24T19:27:13Z
dc.date.issued2022
dc.departmentSiirt Üniversitesi
dc.description.abstractMononuclear transition metal complexes based on ionic liquid have been prepared and characterized in detail. The biological properties of the three complexes were evaluated using radical scavenging activity, reducing power, antibacterial effect, DNA binding and cleavage activity. Among the complexes, [3-[(2R)-2-({[dichloro(eta(6)-benzene)ruthenium]diphenylphosphanyl}oxy)-2-phenylethyl]-1-methyl-1H-imidazol-3-ium chloride] (4), demonstrated the highest radical scavenging (64.7 %) and reducing power activity (0.467) at 200 mu g/ml concentration. The highest zone of inhibition was obtained from [3-[(2R)-2-({[dichloro(eta(6)-p-cymene)ruthenium]diphenyl phosphanyl}oxy)-2-phenylethyl]-1-methyl-1H-imidazol-3-ium chloride] (3), against Bacillus cereus as 14 mm. Furthermore, all complexes were determined to have DNA binding and cleavage activities. Furthermore, theoretical DFT computations have also been carried out for the cationic complexes, to obtain minimum energy configuration of molecules. The effects of the chemical structures of three cationic complexes were also examined in relation to the variable property of electron-donating ligands for ruthenium-based complexes and iridium complex and their potential energy levels in ground and excited states HOMO and LUMO were determined.
dc.description.sponsorshipScience Committee of the Ministry of Education and Science of the Republic of Kazakhstan [IRN AP08857516]; Dicle University [FEN.21.008]
dc.description.sponsorshipThe research is funded by the Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan (Grant No: IRN AP08857516) . Partial supports of this work by Dicle University (Project number: FEN.21.008) is gratefully acknowledged.
dc.identifier.doi10.1016/j.ica.2022.121142
dc.identifier.issn0020-1693
dc.identifier.issn1873-3255
dc.identifier.scopus2-s2.0-85135710722
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1016/j.ica.2022.121142
dc.identifier.urihttps://hdl.handle.net/20.500.12604/6534
dc.identifier.volume542
dc.identifier.wosWOS:000847897700006
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Sa
dc.relation.ispartofInorganica Chimica Acta
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectIonic liquid
dc.subjectBiological assays
dc.subjectHOMO-LUMO
dc.subjectDFT calculation
dc.subjectPhosphinite
dc.subjectIridium
dc.subjectRuthenium
dc.titleTransition metals of arene derivatives with functionalized ionic liquid: DFT investigation, biological applications and electrochemical behavior of complexes
dc.typeArticle

Dosyalar

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu