Effects of Arbutin on Fatty Acid Levels of Erythrocyte and Serum in Wistar Albino Rats Treated with Potassium Bromate

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dc.authoridEkin, Suat/0000-0002-6502-5028
dc.authoridbengu, aydin sukru/0000-0002-7635-4855
dc.contributor.authorAkkoyun, H. Turan
dc.contributor.authorAydin, Sevinc
dc.contributor.authorAkkoyun, Mahire Bayramoglu
dc.contributor.authorBengu, Aydin Sukru
dc.contributor.authorEkin, Suat
dc.contributor.authorErdem, Sinem Aslan
dc.date.accessioned2024-12-24T19:32:56Z
dc.date.available2024-12-24T19:32:56Z
dc.date.issued2022
dc.departmentSiirt Üniversitesi
dc.description.abstractBackground: In the presented study; the Effects of Arbutin (ARB) on the Rat Erythrocyte and serum fatty acid profile which is exposed to potassium bromate (KBrO3) were investigated. Materials and Methods: In this study, 32 Wistar albino rats weighing 250-300 g were used divided into 4 groups. Groups 1: control, group 2: KBrO3 (single dose 100 mg / kg gavage), group 3: ARB (50 mg / kg / day (ip) for 5 days), group 4: KBrO3 + ARB. At the end of the 5(th) day, alteration of fatty acid profile in erythrocyte and serum of rats in all groups was examined. Results: Rat serum essential fatty acid; palmitic acid (C16:0), myristic acid (C14:0), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2), erythrocyte major fatty acids; palmitic acid (C16:0), myristic acid (C14:0), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2), arachidic acid (C20:0), eicosenoic acid (C20:1), and lignoceric acid (C24:0). In addition, in our studied serum and erythrocytes; Total monounsaturated fatty acids (MUFA) varied between 8.91 +/- 0.53- 11.71 +/- 2.55 and 33.71 +/- 2.12- 37.11 +/- 2.12, respectively. It was determined that total polyunsaturated fatty acids (PUFA) varied between 5.90 +/- 1.29- 9.96 +/- 1.18 and 14.72 +/- 3.66- 22.13 +/- 4.82, respectively. Conclusion: In our study, alterations in fatty acid contents were observed, and results suggesting that arbutine affects the enzymes involved in Fatty acid metabolism and has an effect on fatty acid amounts.
dc.identifier.doi10.5530/ijper.56.3.123
dc.identifier.endpage747
dc.identifier.issn0019-5464
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85134075089
dc.identifier.scopusqualityQ3
dc.identifier.startpage740
dc.identifier.urihttps://doi.org/10.5530/ijper.56.3.123
dc.identifier.urihttps://hdl.handle.net/20.500.12604/7888
dc.identifier.volume56
dc.identifier.wosWOS:000826729700016
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAssoc Pharmaceutical Teachers India
dc.relation.ispartofIndian Journal of Pharmaceutical Education and Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241222
dc.subjectArbutin (ARB)
dc.subjectPotassium bromate (KBrO3)
dc.subjectFatty acid (FA)
dc.subjectPolyunsaturated fatty acids (PUFA)
dc.subjectMonounsaturated fatty acids (MUFA)
dc.subjectWistar Albino Rat
dc.titleEffects of Arbutin on Fatty Acid Levels of Erythrocyte and Serum in Wistar Albino Rats Treated with Potassium Bromate
dc.typeArticle

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