Dynamical behavior of tumor-immune system with fractal-fractional operator
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Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Amer Inst Mathematical Sciences-Aims
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
In this paper, the dynamical behavior of the fractional-order cancer model has been analyzed with the fractal-fractional operator, which discretized the conformable cancer model. The fractional-order model consists of the system of nonlinear fractional differential equations. Also, we discuss the fractional-order model to check the relationship between the immune system and cancer cells by mixing IL-12 cytokine and anti-PD-L1 inhibitor. The tumor-immune model has been studied qualitatively as well as quantitatively via Atangana-Baleanu fractal-fractional operator. The nonlinear analysis is used to check the Ulam-Hyres stability of the proposed model. Moreover, the dynamical behavior for the fractional-order model has been checked by using a fractal-fractional operator with a generalized Mittag-Leffler Kernel and verifying the effect of fractional parameters. Finally, the obtained solutions are interpreted biologically, and simulations are carried out to illustrate cancer disease and support theoretical results, which will be helpful for further analysis and to control the effect of cancer in the community.
Açıklama
Anahtar Kelimeler
tumor-immune model, IL-12 cytokin, anti-PD-L1 inhibitor, fractional operator, Mittag-Leffler kernel, existence-uniqueness, Ulam-Hyres stability
Kaynak
Aims Mathematics
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
7
Sayı
5
