Screening for Bioactive Compound Rich Pomegranate Peel Extracts and Their Antimicrobial Activities : Extraction methods for increased antibacterial and antifungal properties

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dc.contributor.authorBalaban, Merve
dc.contributor.authorKoc, Cansel
dc.contributor.authorSar, Taner
dc.contributor.authorAkbas, Meltem Yesilcimen
dc.date.accessioned2024-12-24T19:10:09Z
dc.date.available2024-12-24T19:10:09Z
dc.date.issued2022
dc.departmentSiirt Üniversitesi
dc.description.abstractIn this work, seven different extracts from pomegranate (Punica granatum L., cv. Hicaz nar) peel were prepared by using different solvents (ethanol, methanol, either alone or in combination with acid, acetone and water). The phenolics (punicalagins and ellagic acid), organic acids (citric acid and malic acid) and sugars of pomegranate peel extracts (PPEs) were determined. The highest amounts of punicalagins and ellagic acid were detected by ethanol-acid extract as 13.86% and 17.19% w/v respectively, whereas the lowest levels were obtained with acetone and water extracts. Moreover, the methanol-acid (3.19% malic acid) and ethanol-acid (1.13% citric acid) extracts contained the highest levels of organic acids. The antimicrobial activities of extracts were investigated by agar well diffusion method. Methanol-acid and ethanol-acid extracts exhibited the highest antimicrobial effects on all tested microorganisms, giving inhibition zones ranging in size from 17 mm to 36 mm. Although similar antimicrobial activities were observed by ethanol, methanol and acetone extracts (up to 24 mm), the lowest antimicrobial activities were attained by water extract (0-15 mm). All extracts were generally more effective against Gram-positive bacteria: Enterococcus faecalis, Bacillus subtilis, Bacillus cereus than Gram-negative ones: Escherichia coli and Enterobacter aerogenes (Klebsiella aerogenes). It was shown that extracts from pomegranate peels represent a good source of bioactive compounds. © 2022 Johnson Matthey Public Limited Company. All rights reserved.
dc.identifier.doi10.1595/205651322X16104587974507
dc.identifier.endpage89
dc.identifier.issn2056-5135
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85125006452
dc.identifier.scopusqualityQ2
dc.identifier.startpage81
dc.identifier.urihttps://doi.org10.1595/205651322X16104587974507
dc.identifier.urihttps://hdl.handle.net/20.500.12604/3965
dc.identifier.volume66
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherJohnson Matthey Public Limited Company
dc.relation.ispartofJohnson Matthey Technology Review
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241222
dc.titleScreening for Bioactive Compound Rich Pomegranate Peel Extracts and Their Antimicrobial Activities : Extraction methods for increased antibacterial and antifungal properties
dc.typeArticle

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