Electrochemical behavior of the antineoplastic agent etoposide at a graphene-based modified electrode: Its square-wave adsorptive stripping voltammetric determination in the pharmaceutical formulations

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dc.contributor.authorPinar, Pinar Talay
dc.contributor.authorSaka, Cafer
dc.contributor.authorYardim, Yavuz
dc.date.accessioned2024-12-24T19:09:48Z
dc.date.available2024-12-24T19:09:48Z
dc.date.issued2018
dc.departmentSiirt Üniversitesi
dc.description.abstractAn electrochemical sensor based on the graphene (GR) was prepared, and used for the determination of etoposide (ETO). The electrochemical behaviors of this compound on GR modified glassy carbon electrode (GR/GCE) were investigated by cyclic voltammetry and square-wave adsorptive stripping voltammetry (SWAdSV). Using SWAdSV, a linear calibration curve was obtained for ETO determination in 0.1 M Britton-Robinson (BR, pH 4.0) buffer solution at +0.56 V (vs. Ag/AgCl) (after 30 s accumulation at 0.1 V). A linear relationship was found between peak currents and the concentration of ETO within 0.025 to 0.5 ?g mL -1 , with a detection limit of 0.0023 ?g mL -1 . The developed method was successfully applied to the determination of ETO in the pharmaceutical formulations with good recoveries. © Editura Academiei Romane. All rights reserved.
dc.identifier.endpage1156
dc.identifier.issn0035-3930
dc.identifier.issue12
dc.identifier.scopus2-s2.0-85063751983
dc.identifier.scopusqualityQ4
dc.identifier.startpage1149
dc.identifier.urihttps://hdl.handle.net/20.500.12604/3792
dc.identifier.volume63
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherEditura Academiei Romane
dc.relation.ispartofRevue Roumaine de Chimie
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.titleElectrochemical behavior of the antineoplastic agent etoposide at a graphene-based modified electrode: Its square-wave adsorptive stripping voltammetric determination in the pharmaceutical formulations
dc.typeArticle

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