Investigation of Inhibition Effects of Honey, Pollen, Propolis and Royal Jelly Extracts on Thioredoxin Reductase Enzyme Activity

dc.contributor.authorAkbulut, Gamze
dc.contributor.authorAkkemik, Ebru
dc.date.accessioned2024-12-24T19:16:06Z
dc.date.available2024-12-24T19:16:06Z
dc.date.issued2018
dc.departmentSiirt Üniversitesi
dc.description.abstractThe thioredoxin reductase enzyme is an enzyme that prevents the mechanism of apoptosis from workingand thus triggers the formation of cancer. Therefore, the inhibition of the thioredoxin reductase enzyme isthought to prevent or inhibit cancer. In this study, the effects of extracts of plateau honey, pine honey,chestnut honey, mad or wild honey, pollen, propolis and royal jelly on thioredoxin reductase enzymeactivity were investigated. Enzyme activities were measured at constant substrate and different inhibitorconcentrations to calculate IC50 values. Total antioxidant activity were investigated in order to compare theextracts used in the inhibition study. The strongest inhibitory effect was seen in the pollen methanol extract(IC50 = 2.44?g /mL)
dc.identifier.doi10.16984/saufenbilder.341372
dc.identifier.endpage1590
dc.identifier.issn1301-4048
dc.identifier.issn2147-835X
dc.identifier.issue6
dc.identifier.startpage1585
dc.identifier.trdizinid311315
dc.identifier.urihttps://doi.org/10.16984/saufenbilder.341372
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/311315
dc.identifier.urihttps://hdl.handle.net/20.500.12604/4232
dc.identifier.volume22
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241222
dc.subjectBiyoloji,Onkoloji,Toksikoloji
dc.titleInvestigation of Inhibition Effects of Honey, Pollen, Propolis and Royal Jelly Extracts on Thioredoxin Reductase Enzyme Activity
dc.typeArticle

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