EFFECT OF CARBON TETRACHLORIDE (CCl4) AND ELLAGIC ACID ON RAT ERYTHROCYTE G6PD, 6PGD, GR, GST AND TrxR ENZYME ACTIVITIES

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dc.contributor.authorAKKOYUN H.TURAN
dc.contributor.authorAkkoyun Mahire
dc.date.accessioned2019-11-28T08:45:19Z
dc.date.available2019-11-28T08:45:19Z
dc.date.issued2019en_US
dc.departmentVeteriner Fakültesien_US
dc.description.abstractThe aim of this study was to investigate the effects of carbon tetrachloride and quercetin on selected trace element levels such as Cr (Chromium), Mn (Manganese), Fe (Iron), Cu (Copper) in rats. In the study, 28 male Wistar albino rats (200 +/- 300 g) were used. Rats were divided into 4 groups as Control, CCl4 (carbon tetrachloride), Qu (quercetin), Qu + CCl4 (quercetin + carbon tetrachloride) (n=7 in each group). When Cr (mu g/g) amount was examined an increase was observed in Qu administered group (p <0.01) compared to the control. It was increased in Qu (p <0,05) and CCl4 + Qu (p <0,001) treated groups compared to CCl4 group. Mn decreased in CCl4 and CCl4 + Qu groups compared to control. Fe (mu g/g) content was increased in CCl4, CCl4 + Qu and Qu (p<0.01) groups compared to Control. An increase in Qu treated group compared to CCl4 applied group (p<0.05) was observed. The CCl4 + Qu group decreased compared to the Qu group (p<0.01). Cu content of CCl4 and Qu groups showed an increase whereas CCl4 + Qu applied showed a decrease compared to control. As a result; It is thought that quercetin may have an effect on important trace element levels such as Cr (Chromium) Mn (Manganese), Fe (Iron), Cu (Copper) in the case of oxidative stress caused by carbon tetrachloride.en_US
dc.identifier.endpage6785en_US
dc.identifier.issue9en_US
dc.identifier.startpage6779en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12604/1848
dc.identifier.volume28en_US
dc.institutionauthorAKKOYUN, MAHİRE
dc.language.isoenen_US
dc.relation.ispartofFresenius Environmental Bulletin
dc.relation.publicationcategoryMakale - Uluslararası - Editör Denetimli Dergien_US
dc.rightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.snmz#KayıtKontrol#
dc.subjectCCl4, Quercetin, Trace element, Liveren_US
dc.titleEFFECT OF CARBON TETRACHLORIDE (CCl4) AND ELLAGIC ACID ON RAT ERYTHROCYTE G6PD, 6PGD, GR, GST AND TrxR ENZYME ACTIVITIESen_US
dc.typeArticleen_US

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