Metallo phthalocyanines bearing 2-Isopropyl-6-methylpyrimidin-4-yloxy substituents: synthesis, characterization, aggregation behavior, antioxidant and antibacterial activity, and electronic properties.
Yükleniyor...
Dosyalar
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Zeitschrift für und allgemeine Chemie.
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
A novel phthalonitrile derivative bearing 2-isopropyl-6- methylpyrimidin-4-yloxy substituents at peripheral positions was synthesized by a nucleophilic substitution reaction. Metallophthalocyanines were obtained from the reaction of the novel phthalonitrile with metal Zn, Cu, Co, and Ni salts. The characterization of the compounds was performed using elemental analysis as well as UV/Vis, FT-IR, and 1H-NMR spectroscopy. The aggregation behaviors of phthalocyanine complexes were also investigated. These metallophthalocyanines do not show any aggregation behavior between 10–4–10–6 M concentration range in THF. The antioxidant activities of the synthesized com-pounds were evaluated using three different tests: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, metal chelating activity, and
reducing power assays. All the compounds exhibited various antioxidant activities. In addition, antimicrobial activity of the compounds was tested over four gram positive and two gram negative bacteria. Moreover, the ground-state geometries of the complexes were optimized using density functional theory (DFT) methods at B3LYP/6- 31G(d,p) level in order to obtain information about the 3D arrangements and electronic structure.
Açıklama
Anahtar Kelimeler
Phthalocyanines, Characterization, Aggregation, Antioxidant activity, Antibacterial activity, Electronic structure
Kaynak
Zeitschrift für anorganische und allgemeine Chemie.
WoS Q Değeri
Scopus Q Değeri
Cilt
640
Sayı
10
Künye
Ağırtaş, M. S., Dede, E., Gümüş, S., Dündar, A., & Okumuş, V. (2014). Metallo Phthalocyanines bearing 2‐Isopropyl‐6‐methylpyrimidin‐4‐yloxy Substituents: Synthesis, Characterization, Aggregation Behavior, Antioxidant and Antibacterial Activity, and Electronic Properties. Zeitschrift für anorganische und allgemeine Chemie, 640(10), 1953-1959.
