Melatonin Receptor 1A (MTNR1A) Gene Polymorphism in Cross-Bred Hamdani Sheep: A Preliminary Study

dc.contributor.authorTurgut, Ali Osman
dc.contributor.authorKoca, Davut
dc.date.accessioned2024-12-24T19:18:18Z
dc.date.available2024-12-24T19:18:18Z
dc.date.issued2024
dc.departmentSiirt Üniversitesi
dc.description.abstractMelatonin plays a key role in regulating several vital physiological processes, including the maturation and functioning of the reproductive system, pubertal development, seasonal reproduction, and adaptation. The activation of the melatonin hormone is facilitated by melatonin receptors. This study aimed to investigate melatonin receptor 1A (MTNR1A) gene polymorphism in cross-bred Hamdani sheep. A total of 102 cross-bred Hamdani ewes were used as animal material. DNA was extracted from whole blood. The 824 bp PCR products from the exon II region of the MTNR1A gene underwent analysis for restriction fragment length polymorphism (RFLP) using the RsaI restriction enzyme. In the study, RR, Rr, and rr genotypes were detected for MTNR1A gene in cross-bred Hamdani sheep. Genotype frequencies for RR, Rr, rr were 0.69, 0.27, and 0.04, respectively. Allele frequencies were detected as 0.82 and 0.18 for R and r alleles, respectively. In conclusion, more comprehensive research investigating association between MTNR1A genotypes and reproductive traits should be carried out in cross-bred Hamdani sheep.
dc.identifier.doi10.5281/zenodo.10815493
dc.identifier.endpage133
dc.identifier.issn2717-7238
dc.identifier.issue1
dc.identifier.startpage127
dc.identifier.trdizinid1269344
dc.identifier.urihttps://doi.org/10.5281/zenodo.10815493
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1269344
dc.identifier.urihttps://hdl.handle.net/20.500.12604/5062
dc.identifier.volume8
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofISPEC journal of agricultural sciences (Online)
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241222
dc.subjectBiyoloji,Genetik ve Kalıtım,Veterinerlik
dc.titleMelatonin Receptor 1A (MTNR1A) Gene Polymorphism in Cross-Bred Hamdani Sheep: A Preliminary Study
dc.typeArticle

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