Effect of quercetin on selected micro elements in rat liver tissue during carbon tetrachloride exposure

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dc.contributor.authorTuran Akkoyun, H.
dc.contributor.authorAkkoyun, Mahire Bayramoglu
dc.date.accessioned2024-12-24T19:09:58Z
dc.date.available2024-12-24T19:09:58Z
dc.date.issued2019
dc.departmentSiirt Üniversitesi
dc.description.abstractThe aim of this study was to investigate the effects of carbon tetrachloride and quercetin on selected trace element levels such as Cr (Chromium), Mn (Manganese), Fe (Iron), Cu (Copper) in rats. In the study, 28 male Wistar albino rats (200 ± 300 g) were used. Rats were divided into 4 groups as Control, CCl4 (carbon tetrachloride), Qu (quercetin), Qu + CCl4 (quercetin + carbon tetrachloride) (n=7 in each group). When Cr (ug/g) amount was examined an increase was observed in Qu administered group (p <0.01) compared to the control. It was increased in Qu (p <0.05) and CCl4 + Qu (p <0.001) treated groups compared to CCl4 group. Mn decreased in CCl4 and CCl4 + Qu groups compared to control. Fe (ug/g) content was increased in CCU, CCl4 + Qu and Qu (p<0.01) groups compared to Control. An increase in Qu treated group compared to CCl4 applied group (p<0.05) was observed. The CCl4 + Qu group decreased compared to the Qu group (p<0.01). Cu content of CCl4 and Qu groups showed an increase whereas CCl4 + Qu applied showed a decrease compared to control. As a result; It is thought that quercetin may have an effect on important trace element levels such as Cr (Chromium) Mn (Manganese), Fe (Iron), Cu (Copper) in the case of oxidative stress caused by carbon tetrachloride. © by PSP.
dc.identifier.endpage6763
dc.identifier.issn1018-4619
dc.identifier.issue9
dc.identifier.scopus2-s2.0-85071638000
dc.identifier.scopusqualityN/A
dc.identifier.startpage6757
dc.identifier.urihttps://hdl.handle.net/20.500.12604/3863
dc.identifier.volume28
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherParlar Scientific Publications
dc.relation.ispartofFresenius Environmental Bulletin
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241222
dc.subjectCCl4
dc.subjectLiver
dc.subjectQuercetin
dc.subjectTrace element
dc.titleEffect of quercetin on selected micro elements in rat liver tissue during carbon tetrachloride exposure
dc.typeArticle

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