DNA cleavage properties and synthesis of metallophthalocyanines with 5-methyl-[1, 2, 4] triazolo [1, 5-a] pyrimidin-7-oxy substituents.

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dc.authoridhttps://orcid.org/0000-0002-5505-2700en_US
dc.contributor.authorAğırtaş, Salih
dc.contributor.authorÖndeş, Yusuf
dc.contributor.authorÖzdemir, Sadin
dc.contributor.authorOkumuş, Veysi
dc.date.accessioned2019-12-25T08:15:02Z
dc.date.available2019-12-25T08:15:02Z
dc.date.issued2017en_US
dc.departmentFen - Edebiyat Fakültesien_US
dc.description.abstractThe aim of the present study is to perform synthesis of novel metallophthalocyanines (pcs) with high solubility. The synthesis and characterization of 5-methyl-[1, 2, 4] triazolo [1, 5-a] pyrimidin-7-yloxysubstituted zinc, magnesium, and cobalt pcs are reported. These compounds have been characterized using electronic absorption, nuclear magnetic resonance spectroscopy, infrared, elemental analysis and mass spectra. The aggregation investigations carried out in different concentrations indicate that 5- methyl-[1, 2, 4] triazolo [1, 5-a] pyrimidin-7-yloxy-substituted pc complexes do not have any aggregation behavior for the concentration range of 1 £ 10¡5¡1 £ 10¡6 M in THF. DPPH radical scavenging activity, metal chelating activity, and reducing power of the compounds were evaluated. The DNA gel electrophoresis studies revealed that new phthalonitrile and its metallophthalocyanine compounds cleavaged plasmid DNA (pBR322). Additionally, the ground-state geometries of the complexes were optimized using density functional theory methods at B3LYP/6-31G (d, p) level in order to obtain information about the 3D geometries and electronic structure.en_US
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dc.identifier.citationAğirtaş, M. S., Öndeş, M. Y., Özdemir, S., & Okumuş, V. (2017). DNA cleavage properties and synthesis of metallophthalocyanines with 5-methyl-[1, 2, 4] triazolo [1, 5-a] pyrimidin-7-oxy substituents. Inorganic and Nano-Metal Chemistry, 47(7), 1097-1102.en_US
dc.identifier.endpage1102en_US
dc.identifier.issue7en_US
dc.identifier.startpage1097en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12604/2412
dc.identifier.volume47en_US
dc.institutionauthorOkumuş, Veysi
dc.language.isoenen_US
dc.publisherInorganic and Nano-Metal Chemistryen_US
dc.relation.ispartofInorganic and Nano-Metal Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz#KayıtKontrol#
dc.titleDNA cleavage properties and synthesis of metallophthalocyanines with 5-methyl-[1, 2, 4] triazolo [1, 5-a] pyrimidin-7-oxy substituents.en_US
dc.typeArticleen_US

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