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    Öğe
    Integrating the in vitro antioxidant activity of Polyacrylonitrile/Polyindole composites
    (Wiley, 2024) Alayunt, Naci Omer; Soykan, Cengiz
    In this study, five compounds belonging to the Polymer composites (PCs) family, have been prepared with different amounts of polyacrylonitrile and polyindole in the composite. The PCs have inherently bactericidal activity, owing to the nitrile and indole groups. Antioxidant activity was assessed by using reducing power activity, superoxide radical scavenging activity and hydroxyl radical scavenging activity. In our study, butylated hydroxy toluene (BHT), ascorbic acid and alpha-tocopherol, which are considered synthetic standard antioxidants, were used to compare antioxidant activity. In addition, since it is known that the MDA levels resulting from the oxidation of fats in Saccharomyces cerevisiae yeast cells are inversely proportional to the antioxidant properties, it gave an idea about the in vitro antioxidant properties of the new synthesized PCs. Reducing force capacity, superoxide radical scavenging activity and hydroxyl radical scavenging activity were found to be higher at 100 mu g mL-1 concentration compared to 50 mu g mL-1 concentration. Integrating the In-Vitro Antioxidant Activity of Polyacrylonitrile/Polyindole Composites. image
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    Öğe
    Synthesis, spectroscopic characterization, and in vitro antioxidant activity of polyglycidylmethacrylate/polyindole conducting polymer composites
    (Wiley, 2021) Alayunt, Naci Omer; Soykan, Cengiz
    Polyglycidylmethacrylate/polyindole (PGMA/PIN) conducting polymer composites having five different compositions were prepared chemically using FeCl(3)as an oxidant agent in chloroform solution and nitrogen atmosphere at 10 degrees C. The conducting polymer composites were characterized by FTIR spectroscopic technique, scanning electron microscopy (SEM), atomic force microscopy (AFM), and thermogravimetric analysis (TGA) measurements. It is seen that morphological structure of composite is different from PIN and PGMA. PGMA/PIN conducting polymer composite including 50% of PIN has a nonuniform and less homogenous structure compared to the PIN and PGMA polymer. in vitro antioxidant activity such as reduction force, superoxide radical removal activity, hydroxyl radical trapping activity, MDA measurements inSaccharomyces cerevisiaecells of PGMA/PIN conducting polymer composite was investigated. It was observed that the reduction force capacities decreased as PIN content and increased due to the percentage of composite of PGMA content. in vitro studies of synthesized composites have shown us that these compounds possess new antioxidant properties.