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Öğe Analysis and 3D Imaging of Morphometric - Mineral Structure Changes in Skulls of Male and Female Guinea Pigs During and After Developmental Period(Soc Chilena Anatomia, 2024) Baygeldi, Saime Betul; Yilmaz, Yucehan; Guzel, Baris Can; Kanmaz, Yesim Aslan; Karan, Meryem; Hark, Betul Dagoglu; Yilmaz, SadikEven though morphometric and mineral studies related to the guinea pig (Cavia porcellus) skull have been carried out, this study is the first attempt to evaluate all developmental stages of male and female guinea pigs. This study aims to this study is to create 3D modeling of CT images obtained from the skulls of male and female guinea pigs during the developmental period (prepuberty and the period between puberty and adulthood) and following periods (young adulthood and old adulthood), to analyze some biometric bone data such as volume, surface area and length, and to assess the developmental analysis of the mineral matter change in their skulls. The CT-scanned skulls were transferred to 3D Slicer (5.0.2), which is used for 3D modeling. The surface area and volume were calculated by measuring the measurement points on the models. In addition, the XRF device was used to show elemental ratio changes during different developmental stages. According to metric measurements, a gradual increase was observed during the life period. The metric measurements of the skull bone had a higher measurement value in male guinea pigs than in their female counterparts. While Ca/P ratio increased up to the third group and partially decreased in the fourth group in males, it gradually increased from the first group to the fourth group in females. This study revealed that puberty, adulthood and sex were effective in the physical and chemical characterization of skull bone structure in guinea pigs.Öğe Analysis and 3D Imaging of Morphometric-Mineral Structure Changes in Skulls of Male and Female Guinea Pigs During and After Developmental Period(Universidad de la Frontera, 2024) Baygeldi, Saime Betül; Yilmaz, Yücehan; Güzel, Barıs Can; Kanmaz, Yesim Aslan; Karan, Meryem; Hark, Betül Dagoglu; Yilmaz, SadikEven though morphometric and mineral studies related to the guinea pig (Cavia porcellus) skull have been carried out, this study is the first attempt to evaluate all developmental stages of male and female guinea pigs. This study aims to this study is to create 3D modeling of CT images obtained from the skulls of male and female guinea pigs during the developmental period (prepuberty and the period between puberty and adulthood) and following periods (young adulthood and old adulthood), to analyze some biometric bone data such as volume, surface area and length, and to assess the developmental analysis of the mineral matter change in their skulls. The CT-scanned skulls were transferred to 3D Slicer (5.0.2), which is used for 3D modeling. The surface area and volume were calculated by measuring the measurement points on the models. In addition, the XRF device was used to show elemental ratio changes during different developmental stages. According to metric measurements, a gradual increase was observed during the life period. The metric measurements of the skull bone had a higher measurement value in male guinea pigs than in their female counterparts. While Ca/P ratio increased up to the third group and partially decreased in the fourth group in males, it gradually increased from the first group to the fourth group in females. This study revealed that puberty, adulthood and sex were effective in the physical and chemical characterization of skull bone structure in guinea pigs. © 2024, Universidad de la Frontera. All rights reserved.Öğe Evaluation and 3D imaging of mineral structure changes of the rabbit (New Zealand) skull during developmental periods(Wiley, 2024) Kanmaz, Yesim Aslan; Baygeldi, Saime Betuel; Guezel, Baris Can; Yilmaz, Yuecehan; Karan, Meryem; Hark, Betuel Dagoglu; Yilmaz, SadikThis study aimed to determine the morphometric measurements anatomically and CT images of skulls of healthy male and female rabbits during postnatal development, to analyse the data statistically and to demonstrate the structural changes in bone. A total of 40 rabbits (20 females and 20 males) were divided into four groups including prepubertal period (group I (0-1 month)), period between adolescence and adulthood (group II (3-5 month)) and later (young adult period as group III (1-3 years) and old adult period as group IV (3-5 years)), with five animals in each group. After the morphometric measurements, the surface area and volume values of the skull were calculated. The skulls were reconstructed using a 3D Slicer (5.0.2), which is used for 3D modelling. The cranial bones in each group were then crushed using a grinder so that the powdered samples were obtained for XRF (X-ray fluorescence technique). The p-value was statistically highly significant between group and gender (p < 0.001). In morphometric measurements, males were generally higher than females. Only PL, GBOC and GNB measurements were higher in females. The p-value between groups (in all measurements), between genders (in TL, GLN, FL, VL, OZB and GBN parameters) and between groups and genders (in TL, DL and VL parameters) was statistically highly significant (p < 0.001). The p-value between the groups, p-value between sexes and p-value between group and sex in Si, P, K, Ca, Ni, Zn, Sr, Sr and Ca/P elements were statistically significant (p < 0.001). Consequently, metric, volume and surface area measurements were taken through 3D modelling of skull bone in prepubertal period (group I), period between adolescence and adulthood (group II) and later (young adult period as group III and old adult period as group IV) of rabbits and the change in the mineral structure during postnatal development and effect of sex on this change were investigated. This might be the first study to assess both metric and mineral changes at four age intervals taken during the life span of rabbits.Öğe Physical and chemical characterization of the femur during and after the body development period in male and female guinea pigs(Wiley, 2023) Yilmaz, Yuecehan; Aslan Kanmaz, Yesim; Baygeldi, Saime Betuel; Guezel, Baris Can; Karan, Meryem; Guezel, Fuat; Yilmaz, SadikIn this study, it was aimed to reveal the physical and chemical characterization of the bone structures during body development periods (prepubertal period, period between adolescence and adulthood) and after (young adult period and old adult period) in male and female guinea pigs. In this study, 40 guinea pigs (20 male, 20 female) were used. Morphometric measurements, X-ray fluorescence (XRF) analysis for mineral levels, Brunauer-Emmett-Teller (BET) analysis for surface area, and porosity analysis were applied to the bones. The male guinea pigs had greater values than females in the other three categories, with the exception of the second group, when the females have higher values in morphometric measurements. Ca levels rose up to the third group, as did P levels in the males, peaking in the third group and declining in the fourth. As with phosphorus, there was a progressive rise in females from the first to the fourth group. Fe, Zn, and Sr elements had the greatest values in both genders in the first group. In all four groups, the females had greater Zn levels than males. The highest Ca/P ratio was found in the third male group and the fourth female group. This study revealed that adolescence, adulthood, and gender are effective in the physical and chemical characterization of bone structure in guinea pigs.Öğe Three-dimensional modelling and morphometric analysis of skull of badger (Meles meles) with computed tomography images(Wiley, 2024) Kanmaz, Yesim Aslan; Guzel, Baris Can; Baygeldi, Saime Betuel; Karan, MeryemBackground: Morphometric measurements help to understand the skull morphology in different animal species, detect skull deformations and figure out their causes. Objectives: The aim of this study is to make a three-dimensional (3D) modelling of the badger skull using computed tomography, to show its anatomical structures and to reveal the morphometric measurement values. Methods: Skull measurements were carried out using a digital calliper at 27 measurement points based on metric measurement points. After the scanned images were stored in Digital Imaging and Communications in Medicine format, they were transferred to MIMICS 20.1 (The Materialize Group) programme and 3D models the skulls were created. The surface area and volume values of the skulls were calculated on these models. Results: The volume and surface area parameters were expressed as mean +/- SE. Four different indices were calculated using osteometric measurements. Statistical analyses were made by determining the mean value and standard deviation of the examined properties and the correlation coefficients among these properties. In the metric measurement points taken as a basis, the longest measurement in the skulls was the total length and its mean value was 124.60 +/- 0.64 mm. The shortest measurement was the breadth dorsal to the external auditory meatus, and its mean value was 6.75 +/- 0.24 mm. Conclusions: Consequently, statistical differences in the craniometric values of badgers' skulls were determined by using CT and 3D modelling software. In addition, it was concluded that the badger skull can be easily distinguished from other carnivore species by carrying out morphometric measurements.