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    Analysis of the Association Between Vitamin D Deficiency and Other Diagnoses of Patients by Data Mining Techniques
    (2020) Kaya, Buket; Günay, Abdullah; Özüdoğru, Osman
    One of the most common disorders is vitamin D deficiency. Vitamin D deficiency in individuals with avitamin D level of less than 20 ng / ml has been studied in previous studies, which is also associated withother diagnoses. The aim of this study was to investigate the association of vitamin D deficiency patientswith other diagnoses. In this respect, a data set consisting of patients whose vitamin d levels have beenmeasured in a public hospital for the last 3 years has been provided. Using this data set, the associationrule analysis of data mining techniques was performed. Apriori algorithm was preferred in the analysis.As a result of the analysis, 22 association rules were determined and interpreted.
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    DETERMINATION OF ANXIETY STATUS IN WOMEN WITH CHRONIC DISEASE DURING THE COVID-19 PANDEMIC
    (2022) Büyükbayram, Zeliha; Gül, Sidar; Özüdoğru, Osman
    This study was conducted to determine the anxiety status of women with chronic diseases during the coronavirus disease pandemic. This descriptive study was conducted in February-August 2021 within the internal medicine outpatient clinic of a training and research hospital located in the Southeastern Anatolia Region of Turkey. Individual Descriptive Questionnaire and Spielberger State-Trait Anxiety Inventory forms were used to collect data. The mean state anxiety score of the participants was 46.40±10.46, and the mean trait anxiety score was 49.56±9.33. The trait anxiety mean scores of the participants who have a good relationship with the family and whose health status was not affected during the pandemic was found to lower statistically significant (p<0.05). The trait anxiety mean scores of the participants who have poor economic status was found to higher statistically significant (p<0.05). It was determined that women with chronic diseases had moderate anxiety and were negatively affected by the pandemic process. In line with this information, it comes to the fore that women with chronic diseases need more psychosocial support due to their increased anxiety and they are a group that should be handled with care. It is recommended that more descriptive studies be carried out on this subject.
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    Efficacy of Intravenous Iron Therapy in Female Patients with Iron Deficiency Anemia
    (2023) Güneş, Sevgi; Alayunt, Naci Ömer; Özüdoğru, Osman
    In this study, it was aimed to show the efficacy of intravenous (IV) ferric carboxymaltose treatment for iron deficiency anemia (IDA), which is a public health problem due to its high prevalence in the world and in Türkiye. Since it is the first study in the region, its importance is increasing even more. Eighty female diagnosed with IDA and treated with IV iron carboxymaltose, who applied to Siirt Training and Research Hospital Internal Diseases Polyclinics between June 2018 and September 2019, were included in the study. Biochemical data before and after treatment from the data recorded in the system of the patients who signed the consent form of Siirt University Research Hospital were included in the study retrospectively. After treatment, hemoglobin (HGB), hematocrit (HTC), mean cell volume (MCV), ferritin, iron and B12 values increased statistically (p<0.05). In addition, platelet (PLT), total iron binding capacity (TIBC) and folate values were statistically significantly lower (p<0.05). Additionally, platelet (PLT), total iron binding capacity (TIBC) and folate values were statistically significantly lower (p<0.05). The study is important in terms of revealing the female IDA profile in the region and showing the positive results of IV iron therapy data. It is thought that the study can be a guide in finding solutions to irrational drug use, prolongation of the treatment period and high expenditures while creating IDA treatment protocols.
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    First remarkable findings in comparison of patients in Siirt / Turkey in novel coronavirus(Covid-19) pandemic
    (2020) Alayunt, Naci Ömer; Özüdoğru, Osman; Yerlikaya, Emrah
    In December 2019, a novel coronavirus (Covid-19) associated with human to human transmission and severe human infection has been recently reported from the city of Wuhan in China Hubei Province. The first Covid-19 in Turkey comparative findings of their patients can help spread the infection, early diagnosis, treatment and control. This study in Turkey Siirt State Hospital in Covid-19 diagnosed patients and 12 healthy normal consists of 12 patients. Data from electronic medical records were taken retrospectively and patient and control group data were compared statistically. Statistically decreased lymphocyte (1.23 ± 0.66), WBC (5.00 ± 1.50), neutrophil (3.32 ± 1.77), platelets (175.08 ± 44.18) in Covid-19 patients compared to the control group and increased D-Dimer (595.08 ± 185.87), ferritin (236.31 ± 50.36), CRP (12.43 ± 4.31), lactate (1.37 ± 0.39), CK (189.50 ± 63.66) levels, other clinical findings and CT images were found to be compatible with Covid-19. This study is the first comparative study on pandemic Covid-19 in Siirt/Turkey. These prognostic parameters are important for a specific clinical diagnosis, which may contribute to reflect the evolution of CT findings and the severe course of the disease and the worst clinical picture.
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    Immune plasma therapy in COVID-19 infection: the experience of Siirt
    (2021) Özüdoğru, Osman; Gungormez, Cigdem; Üyüklü, Mehmet
    Objective: COVID-19 pandemic which is rapidly spreading in the world affects people in Turkey significantly. Various drug-methods for treatment are being tried and one of these applications is immune plasma transfusion. Materials and Methods: In this study, 400cc immune plasma treatment was evaluated retrospectively to show the effect of treatment applied to 23 patients with COVID-19 diagnosis in Siirt Training and Research Hospital. Results: It was observed that the use of mechanical ventilation was 47.82% before the immune plasma treatment, while this need decreased to 30.43% after 3 days. Nine out of 23 patients who received immune plasma therapy recovered by completing their treatment. Conclusion: Although the immune plasma applied on patients contributes to the recovery of patients, the evidence is yet insufficient. Therefore, more COVID-19 patients need to be observed to document the efficiency of immune plasma transfusion therapy.
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    Psychological and biochemical Impact of Covid-19 pandemic on health workers in Siirt, Turkey
    (2021) Alayunt, Naci Omer; Özüdoğru, Osman; Cakan, Ergul
    The aim of this study was to analyze the anxiety level of health care workers at the forefront of the fight against Covid-19 and to determine the prevalence of psychiatric symptoms of factors contributing to psychological stress and to identify risks and preservatives. To determine the anxiety levels of healthcare workers and the factors that contribute to psychological stress in the fight against Covid-19. After receiving ethical and legal permissions Necessary Siirt, a total of 150 people working in training and Research Hospital Covid-19 pandemic pandemic 50 to 100 active employee in the service of medical personnel and medical personnel outside the service running status among sociodemographic trait anxiety (Beck anxiety scale and the impact of Event Scale), a survey study was conducted with the questions the reasons. In this study, the effect scores of events in the pandemic service were found to be different at p<0.001 level compared to non-pandemic. At the same time, anxiety scores in the pandemic service were found to be different at the level of p<0.001 compared to non-pandemic. It was consistent with previous studies on the biochemical findings of healthcare workers who contracted Covid-19. In this context, administrators' attentive behavior towards psychological, psychological and psycho-social needs, stabilization of anxiety, and programs that teach relaxation techniques can help healthcare professionals develop self-help skills during periods of increased stress.
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    Seropositivity of HBsAg, Anti-HBs, Anti-HCV and Anti-HIV in patients admitted to Siirt Training and Research Hospital
    (2022) Acer, Ömer; Özüdoğru, Osman
    ABSTRACT Objective: Viral hepatitis infections, including hepatitis B and C, and HIV represent an important public health problem worldwide. In this study, we aimed to investigate the seropositivity of HBsAg, Anti-HBs, Anti-HCV, and Anti-HIV in patients who applied to our hospital between 2019 and 2021. Methods: In this study, the frequency of HBsAg, Anti-HBs, total Anti-HCV and anti-HIV in patients admitted to our hospital between January-2019-January 2021 was evaluated retrospectively. Results: HBsAg positivity was determined as 3.28% in a total of 52420 patients. HBsAg positivity was found to be 4.12% (95%CI: 3.9-4.3) in males, whereas 2.67% (95%CI 2.56-2.78) in females. There was a statistically significant relationship between HBsAg positivity and gender and age (p<0.001). Anti-HBs level of 54.9% of the patients (95%CI: 44.6-45.6) was found to be sufficient for immunity (Anti-HBs >10 mIU / ml). While this rate was found to be 61.04% (95%CI: 60.5-61.5) in males, it was found to be 50.37% (95%CI: 50-50.7) in females. A significant relationship was found between Anti-HBs positivity and gender and age (p<0.001). General Anti-HCV positivity was found as 0.11% (95%CI: 0.09-1.01). There was significant relationship between age groups for anti-HCV positivity (p<0.001), whereas the relationship for gender was not significant (p=0.934). There was no statistically significant relationship between anti-HIV positivity and age (p=0.307) and gender (p=0.999). Anti-HIV positivity was determined as 0.3‰ (95%CI: 0.01-1.05). Conclusion: As a result, viral hepatitis is an important health problem around the world and for our city. Vaccination, infection control programs, and public education can reduce the risk of new infections. Anti-HIV positivity was found to be very low in our city.
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    Siirt İlindeki Bruselloz Tanılı 112 Hastanın Retrospektif Olarak Değerlendirilmesi
    (2021) Özüdoğru, Osman; Acer, Ömer Acer
    Amaç: Bu çalışmada bruselloz olgularının epidemiyolojik, klinik, laboratuvar bulguları ve uygulanan tedavi rejimlerinin değerlendirilmesi amaçlanmıştır. Materyal ve Metot: Çalışmada Mart 2018-Haziran 2019 tarihleri arasında Siirt devlet hastaneleri polikliniklerinde bruselloz tanısı konulan 112 hasta retrospektif olarak incelenmiştir. Bruselloz olgularının epidemiyolojik, klinik, laboratuvar bulguları ve uygulanan tedavi rejimleri değerlendirilmiştir. Bulgular: Çalışmaya dahil edilen 112 olgunun %38,4’ünün erkek, %61,6’sının kadın olduğu tespit edildi. Yaş ortalamaları ise 38,1 (18–76) yıl olarak tespit edilmiştir. Hastaların %56’sı köylerden, %19’u ilçelerden ve %37’si şehirden başvurmuştur. Hastaların ilk başvuru anındaki en sık yakınmaları; vücut ağrısı, eklem ağrısı, halsizlik, ateş, baş ağrısı ve bel ağrısı olarak saptanmıştır. Fizik muayenelerinde hastaların %30,1’inde artrit, %78,8’inde artralji, %84,1’inde miyalji %9,7’sinde hepatomegali %8’inde splenomegali ve %2,7’sinde lenfadenopati saptanmıştır. Hastaların %12,4’ünde lökopeni, %7,1’inde lökositoz, %33,6’sında anemi ve sadece %2,7’sinde polistemi saptanmıştır. Brucella Coombs aglütinasyon testi 14 olguda 1/320, 20 olguda 1/640, 25 olguda 1/280, 17 olguda 1/2560 ve 36 olguda 1/5120’nin üzerinde saptandı. Hastaların %46,9’unda karaciğer enzim yüksekliği, %54,9’unda eritrosit sedimantasyon hızı yüksekliği, %33,6’sında CRP yüksekliği saptanmıştır. Hastalara ağırlıklı olarak doksisiklin + rifampisin, doksisiklin + rifampisin + seftriakson, vedoksisiklin + seftriakson tedavileri uygulanmıştır. Tedavi sonrasında ise hastaların %63,44’ünde Brucella Coombs aglütinasyon testi negatif sonuç vermiştir. Sonuç: Sonuç olarak çalışmamızdan elde ettiğimiz bulgular, hayvancılığın yoğun olarak yapıldığı Siirt ilimizde brusellozun görülme sıklığının hala yüksek olduğunu göstermektedir. Ayrıca endemik bölgelerde ateş, eklem ağrısı, halsizlik gibi özgün olmayan yakınmalarla gelen hastalarda bruselloz ayırıcı tanıda düşünülmelidir.