Siirt Üniversitesi Kurumsal Akademik Arşivi
DSpace@Siirt, Siirt Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Effects of Washing Dirty Eggs of Geese with Boric Acid and Vinegar on Hatchability and Microbial Loads
(Pakistan Agricultural Scientists Forum, 2025-02-22) Eroglu, M; Erisir, Z; Simsek, U. G.; Mutlu, S. Iflazoglu; Baykalir, Y.; Gungoren, A.
This study aimed to evaluate whether washing dirty goose eggs with tap water, vinegar, and boric acid solutions could improve hatching performance and reduce microbial load. A total of 3,360 eggs were used for hatching performance assessments, while 84 eggs were analyzed for microbiological parameters. The study consisted of seven treatment groups: physically clean eggs (PC), unwashed dirty eggs (NC), eggs washed in tap water (TW), eggs washed with a vinegar solution containing 2% acetic acid (S2), eggs washed with a vinegar solution containing 4% acetic acid (S4), eggs washed with a 2% boric acid solution (B2), and eggs washed with a 4% boric acid solution (B4). Hatchability of set eggs and hatch of fertile eggs improved significantly in the PC, S2, and B2 groups (P<0.01). Embryonic mortality was significantly low in the PC and B2 groups (P<0.05). Significant differences were observed between the groups for total mesophilic aerobic bacteria (TMAB) (P<0.001), total coliforms (TCN) (P<0.01), and Escherichia coli (P<0.01). The lowest TMAB counts were recorded in the S2 and B4 groups, while the lowest TCN counts were observed in the B4 group. Bacterial analysis of egg contents showed that all bacterial groups were below detectable limits. In conclusion, washing dirty goose eggs with tap water, vinegar, or boric acid solutions (2% and 4%) effectively reduced the microbial load on the eggshell for all examined microorganisms and significantly improved hatching parameters compared to dirty eggs.
The Effect of Cognitive Behavioral Therapy-Based Psychoeducation on Anger Control and Cognitive Flexibility in İndividuals Convicted of Homicide
(SAGE Publications, 2025-05-08) Sabri Toğluk; Funda Kavak Budak
This study aims to determine the effect of Cognitive Behavioural Therapy (CBT)-based psychoeducation on anger control and cognitive flexibility in individuals convicted of homicide. The study was completed with 47 individuals convicted of murder (23 control, 24 experimental) in the form of pretest-posttest control group experimental design. The experimental group received eight sessions of psychoeducation, while the control group received no intervention. The data was collected using the personal information form, controlled anger scale (CAS), and cognitive flexibility inventory (CFI). The data was analyzed by number, percentage distribution, and paired samples t-tests. After CBT-based psychoeducation, anger control and cognitive flexibility scores of the individuals in the experimental group increased compared to the individuals in the control group. In addition, it was determined that the difference between the pre-test and post-test total mean scores of CAS and CFI of the individuals in the experimental group was statistically significant (p < .05). In addition, it was determined that CBT-based psychoeducation had a "large" effect size of CAS (2.01) and CFI (1.06).
Characteristic of the excretory system in Cassida palaestina Reiche, 1858 (Coleoptera: Chrysomelidae: Cassidinae)
(Springer Science and Business Media LLC, 2025-05-06) Mesut Sırrı; Damla Amutkan Mutlu
The Malpighian tubules are well-known and studied as the principal excretory organs in most insects. They play a key role in the production of primary urine and osmoregulation. It works with the rectum while regulating the water and salt balance in the body. The distal ends of the tubules are found in contact with the wall of the rectum in insects that feed on dry substances or live in a nearly dry environment and therefore, need to retain water: that is an arrangement known as a cryptonephric system. In this study, Cassida palaestina Reiche, 1858 is a beetle species belonging to the order Coleoptera was used as material, and the morphological features of the Malpighian tubules of this species were examined using light microscopy and scanning electron microscopy. The four cryptonephric Malpighian tubules of C. palaestina are found at the junction of the midgut and hindgut. The apical surface of tubule cells is surrounded by numerous microvilli. The cytoplasm of tubule cells fills with granules of many different sizes. Here, we reported our observations on the cryptonephridial complex in C. palaestina, and this study is almost the first study to examine the structure of the excretory system of the genus Cassida. Insights into the structure of the cryptonephridial complex of this species are compared with the well-studied cryptonephridial complexes of Cucujiformia. The findings were found to be quite similar to those of other species studied in the literature (with the structure of the Malpighian tubules of insects within the same order and from different orders). These data are the basis for future morphological studies. At the same time, the presence or absence of the cryptonephridial complex among species in the Cucujiformia infraorder, which C. palaestina is a part of, helps to understand the phylogenetic relationship.
Equipping Police officers with resources: perceived control of internal states and suicide tendencies among Turkish Police officers, unraveling the serial mediating roles of resilience and depression
(Springer Science and Business Media LLC, 2025-05-08) Mehmet Ali Padır; Caner Doğrusever; Bülent Tansel; Mehmet Sıddık Vangölü
Drawing from existing literature, this study highlights police officers' heightened vulnerability to depression and suicidality as a result of occupational stressors and investigates the intricate associations among Turkish police officers' perceived control of internal states (PCOIS), resilience, depression, and suicidal tendencies. The study uses a comprehensive analysis to investigate how PCOIS influences resilience and depression, which subsequently impact suicidal tendencies. A total of 628 police officers participated in the study voluntarily. The mediation analyses indicate individuals with high PCOIS levels tend to have higher resilience, thus leading to lower suicidality regardless of depression levels. High PCOIS levels have also been linked to lower depression levels, thus also leading to a decrease in suicidality independent of resilience. The study shows both resilience and depression to be affected by PCOIS levels, with resilience acting as a protective shield against suicidality, whereas depression exacerbates the likelihood of suicidality. Lastly, the study has uncovered a serial mediating effect, with higher PCOIS levels enhancing resilience and subsequently reducing depression and suicidal tendencies. Therefore, resilience and depression play crucial roles as serial mediators in the relationship between PCOIS and suicidality, underscoring PCOIS's importance in psychological interventions aimed at bolstering resilience and mitigating depression and suicidality among police officers. This study contributes uniquely to the literature by demonstrating PCOIS's protective role in a high-stress profession and provides practical implications for developing targeted mental health interventions.
Rating of in vitro cytotoxicity activities and anti-xanthine oxidase activities of some non-proteoneogenic amino acid derivatives by molecular docking and molecular dynamics studies
(Elsevier BV, 2025-09) Zuhal Alım; Serap Yalçın Azarkan; Namık Kılınç; Ebru Akkemik
Hyperuricemia is a chronic disease closely associated with many pathological conditions, including cancer, which occur due to increased uric acid levels. Xanthine Oxidase (XO) facilitates the stepwise conversion of hypoxanthine to xanthine and subsequently to uric acid, serving a crucial function in purine metabolism. XO inhibitors are the most important therapeutic agents for the control of hyperuricemia. The fact that existing XO inhibitors have serious side effects has made it necessary to describe original, impressive inhibitors with minor side effects. In this study, since the close relationship between hyperuricemia and cancer, the inhibition effects of some non-proteogenic amino acid derivatives (1-4) on XO activity and their cytotoxic effects on triple-negative breast cancer cell line (MDA-MB-231) were examined together. The inhibition effects of molecules 1-4 on XO activity were determined by IC50 values, and for XO, IC50 values of 1-4 were found to be 1.338 µM, 1.357 µM, 1.788 µM, 1.228 µM respectively. The cytotoxic effect of the molecules (1-4) on MDA-MB-231 cell lines was investigated by XTT analysis. According to the results obtained, it is seen that the effect of the 2nd (IC50:98.55 µM) molecule is more toxic on the cells than the others and molecule 2 demonstrated significant inhibition of cell migration in MDA-MB-231 cells in a compared to the untreated control. The study was supported by molecular docking and molecular dynamics and ADME analyses. In conclusion, the results of this study may be useful in the design of XO inhibitor drugs for the treatment of hyperuricemia by contributing to the synthesis of new, effective amino acid-derived XO inhibitors with fewer side effects.
