Siirt Üniversitesi Kurumsal Akademik Arşivi
DSpace@Siirt, Siirt Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Theoretical and numerical investigation of a memristor system with a piecewise memductance under fractal–fractional derivatives
(Walter de Gruyter GmbH, 2025-01-01) Maroua Amel Boubekeur; İrem Akbulut Arik; Seda İğret Araz
This research deals with the theoretical and numerical investigations of a memristor system with memductance function. Stability, dissipativity, and Lyapunov exponents are extensively investigated and the chaotic tendencies of the system are studied in depth. The memristor model, where a piecewise memductance function is incorporated, is modified with fractal-fractional derivatives with exponential decay, power law, and Mittag-Leffler kernels, which provide powerful tools for modeling complex systems with memory effects, long-range interactions, and fractal-like behavior. Employing the Krasnoselskii-Krein uniqueness theorem and the fixed point theorem, the existence and uniqueness of the solutions of the model including fractal-fractional derivatives with the Mittag-Leffler kernel are proven. The fractal-fractional derivative model is solved numerically using the Lagrange polynomial approach, and the chaotic tendencies of the system are exhibited through numerical simulations. The findings indicated that the memristor model with fractal-fractional derivatives was observed to exhibit chaotic behavior.
Discovery of host genetic factors through multi-locus GWAS against toxoplasmosis in sheep: addressing one health perspectives
(Springer Science and Business Media LLC, 2025-04-12) Yalçın Yaman; Veysel Bay; Yiğit Emir Kişi
Toxoplasma gondii stands as one of the most successful pathogens, capable of infecting nearly all warm-blooded species. It is estimated that up to 50% of human population might harbor Toxoplasmosis infections. One of the primary transmission routes is the consumption of tissue cysts from infected farm animals used for food production. Thus, controlling Toxoplasmosis in farm animals is of vital importance for human health and food safety. Selective breeding in farm animals, where available, could complement classical control measures like biosecurity measures, vaccination, and test-and-cull methods. This multidisciplinary approach will make the eradication of Toxoplasmosis more effective. For this purpose, we conducted four multi-locus genome-wide association (GWA) approaches to identify the polygenic factors underlying innate resistance to Toxoplasma gondii in naturally infected sheep. Our findings indicate that 16 single nucleotide polymorphisms (SNPs), exhibiting varying degrees of statistical power, play a significant role in host immunity against T. gondii infection. We propose the genes containing these SNPs or located within 100 ± Kb of them (PLSCR5, EPHA3, DGKB, IL12B, CGA, WDR64, TMEM158, CLMP, and SIAE) as potential candidate genes. This study represents the first exploration of host genetic factors against Toxoplasmosis in livestock, utilizing the ovine paradigm as its foundation.
The effects of progressive muscle relaxation exercises on premenstrual syndrome symptoms and violence tendencies in women: a randomized controlled trial
(Springer Science and Business Media LLC, 2025-04-12) Sabri Toğluk; Sidar Gül
Background: Although violence is reported in women with premenstrual syndrome (PMS), preventive interventions are among the essential responsibilities of nurses. This study aimed to determine the effect of progressive muscle relaxation exercises (PMRE) given to women with PMS on PMS symptoms and violent tendencies.
Methods: The study was conducted experimentally with a pre-test/post-test control group between January and August 2024 in a province located in the southeastern Anatolia region of our country. The study included 106 participants, 53 experimental and 53 control, who had PMS. Participants were provided with a PMRE application for eight weeks. Data were collected through the 'Personal Information Form, PMS Scale and Violence Tendency Scale (VTS).' Data were analysed using descriptive statistics, chi-square, independent samples t-test and one-way multivariate analysis of variance.
Results: Participants in the intervention group had significantly lower mean scores on the post-test PMS scale and the VTS than participants in the control group (p < 0.05). The difference between the PMS scale's pre-test and post-test mean scores was statistically significantly lower in the experimental group (P < 0.001). The difference between the groups was statistically significant in terms of the combined dependent variables, including the pre-test and post-test change in the mean scores of the PMS scale and the VTS (F(2,103) = 158.77, P < 0.001; V = 0.245; ηp2 = 0.755). This difference explained 75.5% of the variance in the dependent variable.
Conclusion: PMRE administration has a high level of efficacy in reducing PMS and violence tendencies.
Evaluation of salivary BDNF levels in gingivitis and periodontitis: a preliminary research
(Springer Science and Business Media LLC, 2025-04-10) Veysel Tahiroglu; Emrah Yerlikaya; Revsa Evin Canpolat Erkan; Hasan Karagecili; Azat Sagin; Nushet Sagin
Background: Oral health is closely related to physical health, life comfort, and functional needs. Gingivitis is a condition that means hardening of the gum tissue, prone to redness, swelling, or bleeding due to different reasons. Periodontitis damages the soft tissue around the teeth. It is a serious gum infection that destroys the bone that supports a person's teeth, if left untreated. BDNF is a member of the neurotrophin family, playing roles in the survival, growth, and function of neurons in the central and peripheral nervous system. This study aims to determine and compare salivary BDNF levels in individuals with periodontal disease and healthy controls, and to assess its relationship with clinical periodontal parameters.
Methods: After the participants were informed and their consent was obtained, unstimulated saliva samples were taken. In our study, experimental and control groups were formed with 30 people in each group. BDNF level was measured in the saliva samples taken.
Results: We found no statistically significant difference in age and gender between the healthy group, gingivitis group, and periodontitis group. There was a significant difference in the PI, GI, PPD, CAL, and BOP values in all three groups. No statistically significant difference was found when salivary BDNF levels of the groups included in the study were compared.
Conclusions: Demographic and clinical findings recorded in this study support that the amount of BDNF partially affects periodontal health parameters and neurological diseases.
Preserving Quality and Extending Shelf Life of Climacteric Persimmon Fruits Using Melatonin and Modified Atmosphere Packaging
(Wiley, 2025-04) Emine Kucuker; Muttalip Gundogdu; Emrah Güler; Ahmet Sumbul; Onur Tekin; Bulent Hallac
Quality and product losses during the postharvest storage of climacteric persimmon fruits pose significant challenges due to their short shelf life and limited marketing period. This study examined the effects of melatonin (1 mM) and modified atmosphere packaging (MAP) on preserving the quality, biochemical properties, and organic acid contents of persimmons, as well as extending their shelf life during storage at 0°C ± 0.5°C. The MAP resulted in the lowest weight loss, recording only 6.63%. The combination of melatonin and MAP provided the highest fruit firmness at 8.69 kg/cm2, along with a total antioxidant level of 12.40 μmol TE 100 g-1. Additionally, this treatment improved total phenolic content and most individual organic acids, except for fumaric acid, which was highest in the MAP treatment. The organic acid contents of the fruits varied during storage, depending on the specific acid. Malic acid was the predominant organic acid and was consistently better preserved by the treatments compared to the control. It is important to note that the reduction in malic acid was approximately 1.5 times less in the treated fruits than in the controls, while the decline of other organic acids was 3-4 times greater. In conclusion, both MAP and the combination of melatonin and MAP were effective methods for preserving the quality attributes and extending the shelf life of persimmon fruits.
