Synthesis, characterization and first application of chiral C2-symmetric bis(phosphinite)-Pd(II) complexes as catalysts in asymmetric intermolecular Heck reactions

Karakas, Duygu ElmaDurap, FeyyazAydemir, MuratBaysal, Akin2024-12-242024-12-2420160268-26051099-0739https://doi.org/10.1002/aoc.3416https://hdl.handle.net/20.500.12604/5839A series of new chiral C-2-symmetric bis(phosphinite) ligands and their palladium(II) complexes have been synthesized and for the first time used as catalysts in the palladium-catalysed asymmetric intermolecular Heck coupling reactions of 2,3-dihydrofuran with iodobenzene or aryl triflate. Under optimized conditions, products were obtained with high conversions and moderate to good enantioselectivities. The new C-2-symmetric bis(phosphinite) ligands and their palladium(II) complexes were characterized using multinuclear NMR and Fourier transform infrared spectroscopies and elemental analysis. Copyright (c) 2015 John Wiley & Sons, Ltd.eninfo:eu-repo/semantics/closedAccesspalladium(II)C-2 symmetryphosphiniteasymmetric Heck couplingSynthesis, characterization and first application of chiral C2-symmetric bis(phosphinite)-Pd(II) complexes as catalysts in asymmetric intermolecular Heck reactionsArticle304193198Q2WOS:000372924700004Q12-s2.0-8495343281910.1002/aoc.3416