Faizan, MohammadAlam, PravejKumari, AshaSuresh, GaliSharma, PriyankaKarabulut, FadimeSoysal, Sipan2024-12-242024-12-2420242667-064Xhttps://doi.org10.1016/j.stress.2024.100615https://hdl.handle.net/20.500.12604/4086Heavy metal (HM) toxicity of agricultural soils poses a major risk to plant health, human life, and global food chain. Crop output and health are negatively impacted when HM levels in agricultural soils reach hazardous points. The nano-biochar (nano-BC) mediated stress tolerance has attracted growing scientific interest because biochar has the potential to be a novel and sustainable solution that may be actively included into the development of sustainable agriculture and food production. At present, biochar is extensively employed as a powerful tool to enhance sustainable agriculture with minimal impact on ecosystems and the environment. Nano-BC offers improved surface area, adsorption and mobility properties in soil compared to traditional fertilizers. Furthermore, nano-BC may prove to be the most practical substitute for traditional waste management techniques because of its affordability, sustainability, and environmental friendliness. In this review, we examine the application of nano-BC in the regulation of HM stress tolerance for improving plant growth and development. We focus on the impact of HMs impact on crop productivity, nano-BC amendments, their application, and production. The article also explores the nano-BC risk and toxicity. Through the perspective of multidisciplinary research, this work highlights the significance of nano-BC as cutting-edge tools in the field of agriculture, igniting a paradigm shift toward sustainable and stress-resilient farming systems. © 2024 The Author(s)eninfo:eu-repo/semantics/openAccessHeavy metalNano-biocharPhysiological roleStress toleranceUnraveling the nano-biochar mediated regulation of heavy metal stress tolerance for sustaining plant healthReview Article14Q12-s2.0-8520514479610.1016/j.stress.2024.100615